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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR69
All Species:
20.3
Human Site:
S226
Identified Species:
34.36
UniProt:
Q8N136
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N136
NP_849143.1
415
45777
S226
S
A
E
I
I
S
L
S
F
N
T
S
G
D
R
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
Q222
T
I
K
M
W
E
V
Q
T
G
Y
C
V
K
T
Rhesus Macaque
Macaca mulatta
XP_001102911
493
54175
S304
S
A
E
I
I
S
L
S
F
N
T
S
G
D
R
Dog
Lupus familis
XP_534593
415
45968
S226
S
A
E
I
I
S
L
S
F
N
T
S
G
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV4
629
70529
Q430
V
A
A
V
R
C
V
Q
Y
D
G
R
R
V
V
Rat
Rattus norvegicus
Q5BK30
415
45841
S226
L
A
E
I
I
S
L
S
F
D
T
S
G
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514877
244
26944
V56
H
I
L
P
L
T
N
V
A
F
N
K
S
G
S
Chicken
Gallus gallus
Q9PTR5
410
46646
Q222
T
I
K
M
W
E
V
Q
T
G
Y
C
V
K
T
Frog
Xenopus laevis
Q5FWQ6
415
45899
S226
A
A
E
I
I
S
L
S
F
N
T
T
G
D
R
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
C226
F
A
E
I
I
S
L
C
F
N
T
T
G
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
S173
P
Q
S
N
L
I
V
S
G
S
F
D
E
S
V
Honey Bee
Apis mellifera
XP_394888
416
46448
H226
T
A
E
I
I
A
L
H
F
N
N
D
G
N
Q
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
S188
P
Q
S
S
L
V
V
S
G
S
F
D
E
S
V
Sea Urchin
Strong. purpuratus
XP_782357
392
43254
F204
A
E
I
I
S
L
S
F
N
S
M
G
D
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.7
77
92.5
N.A.
21.6
89.8
N.A.
45
28.1
80
73.2
N.A.
24.5
54.3
22.8
70.6
Protein Similarity:
100
45
79.7
97.5
N.A.
39.1
95.1
N.A.
50.3
45.2
90.1
86.7
N.A.
43.8
72.1
40.4
81.9
P-Site Identity:
100
0
100
100
N.A.
6.6
86.6
N.A.
0
0
86.6
80
N.A.
6.6
53.3
6.6
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
33.3
93.3
N.A.
13.3
26.6
100
86.6
N.A.
26.6
80
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
58
8
0
0
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
15
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
0
22
8
43
0
% D
% Glu:
0
8
50
0
0
15
0
0
0
0
0
0
15
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
50
8
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
15
8
8
50
8
0
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
22
8
58
50
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
0
0
0
0
0
0
0
8
0
15
0
% K
% Leu:
8
0
8
0
22
8
50
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
8
43
15
0
0
8
0
% N
% Pro:
15
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
22
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
8
8
8
43
% R
% Ser:
22
0
15
8
8
43
8
50
0
22
0
29
8
15
8
% S
% Thr:
22
0
0
0
0
8
0
0
15
0
43
15
0
0
15
% T
% Val:
8
0
0
8
0
8
36
8
0
0
0
0
15
8
29
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _