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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GJD3 All Species: 6.36
Human Site: S278 Identified Species: 15.56
UniProt: Q8N144 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N144 NP_689343.3 294 31933 S278 A S L R E C G S G R G K A S P
Chimpanzee Pan troglodytes XP_001170351 293 31749 S277 A S L R E C G S G R G K A S P
Rhesus Macaque Macaca mulatta XP_001097415 295 32523 C275 K T E L D A C C F P R E S T S
Dog Lupus familis XP_543178 447 48624 P276 A V T I G F P P F S A P S A S
Cat Felis silvestris
Mouse Mus musculus Q91YD1 278 30202 G260 A G D S E G E G G S G H S K A
Rat Rattus norvegicus P29414 416 45994 T291 P T V Q G K A T G F P G A P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518826 459 50297 A349 S N Q H I L T A E Q N W A N Q
Chicken Gallus gallus P18860 369 41726 A281 P D F N Q C L A S P N G K F I
Frog Xenopus laevis P51914 352 40615 K337 K T H S T V E K A S T R A S S
Zebra Danio Brachydanio rerio Q92052 380 43560 G355 S S S P E S N G T A V E Q N R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 86 32.8 N.A. 81.2 33.4 N.A. 32 35.2 32.3 33.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 86.4 42.7 N.A. 85.3 44.4 N.A. 42.2 48.2 47.1 47.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 26.6 13.3 N.A. 6.6 6.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 20 N.A. 33.3 40 N.A. 40 20 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 0 0 10 10 20 10 10 10 0 50 10 10 % A
% Cys: 0 0 0 0 0 30 10 10 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 40 0 20 0 10 0 0 20 0 0 0 % E
% Phe: 0 0 10 0 0 10 0 0 20 10 0 0 0 10 0 % F
% Gly: 0 10 0 0 20 10 20 20 40 0 30 20 0 0 0 % G
% His: 0 0 10 10 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 20 0 0 0 0 10 0 10 0 0 0 20 10 10 0 % K
% Leu: 0 0 20 10 0 10 10 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 0 10 0 0 0 20 0 0 20 0 % N
% Pro: 20 0 0 10 0 0 10 10 0 20 10 10 0 10 20 % P
% Gln: 0 0 10 10 10 0 0 0 0 10 0 0 10 0 10 % Q
% Arg: 0 0 0 20 0 0 0 0 0 20 10 10 0 0 10 % R
% Ser: 20 30 10 20 0 10 0 20 10 30 0 0 30 30 30 % S
% Thr: 0 30 10 0 10 0 10 10 10 0 10 0 0 10 0 % T
% Val: 0 10 10 0 0 10 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _