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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGI3
All Species:
36.36
Human Site:
S446
Identified Species:
88.89
UniProt:
Q8N145
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N145
NP_644807.1
548
61704
S446
L
S
R
Y
I
G
D
S
K
I
L
R
W
E
G
Chimpanzee
Pan troglodytes
Q1EGL0
548
61688
S446
L
S
R
Y
I
G
D
S
K
I
L
R
W
E
G
Rhesus Macaque
Macaca mulatta
XP_001106283
675
75127
S573
L
S
R
Y
I
G
D
S
K
I
L
R
W
E
G
Dog
Lupus familis
XP_543254
653
72365
S551
L
S
R
Y
I
G
D
S
K
I
L
R
W
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K406
548
61799
S446
L
S
R
Y
I
G
D
S
K
I
L
R
W
E
G
Rat
Rattus norvegicus
Q8K4Y5
557
63709
S455
L
T
R
F
I
G
D
S
K
V
M
K
W
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513725
484
55978
T393
K
W
D
S
K
Q
F
T
E
I
Q
A
L
P
S
Chicken
Gallus gallus
NP_001038120
526
60552
S424
L
T
R
F
I
G
D
S
K
V
M
K
W
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034768
551
63642
S448
L
T
R
F
I
G
D
S
K
I
L
R
W
D
N
Tiger Blowfish
Takifugu rubipres
NP_001072088
522
59837
S419
L
T
R
F
I
G
D
S
K
I
L
R
W
E
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
79.4
81.6
N.A.
96.5
51.1
N.A.
45.6
50.7
N.A.
58
56.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
80.3
82.8
N.A.
98.1
70.7
N.A.
63.8
69.7
N.A.
76.2
72.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
60
N.A.
6.6
60
N.A.
73.3
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
90
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
60
0
% E
% Phe:
0
0
0
40
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
90
0
0
0
0
0
0
0
20
80
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
90
0
0
0
0
80
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
90
0
0
20
0
0
0
% K
% Leu:
90
0
0
0
0
0
0
0
0
0
70
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
90
0
0
0
0
0
0
0
0
70
0
0
0
% R
% Ser:
0
50
0
10
0
0
0
90
0
0
0
0
0
0
10
% S
% Thr:
0
40
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
90
0
0
% W
% Tyr:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _