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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1967 All Species: 24.55
Human Site: S274 Identified Species: 54
UniProt: Q8N163 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N163 NP_066997.3 923 102902 S274 F P L S Q P F S L H H P S R I
Chimpanzee Pan troglodytes XP_519650 1152 127379 S503 F P L S Q P F S L H H P S R I
Rhesus Macaque Macaca mulatta XP_001106923 965 106846 S316 F P L S Q P F S L H H P S R I
Dog Lupus familis XP_543248 918 102116 S274 F P L S Q P F S L H P P S R I
Cat Felis silvestris
Mouse Mus musculus Q8VDP4 922 102984 S274 F P L G Q P F S L H H P S R I
Rat Rattus norvegicus NP_001163943 922 102775 S274 F P L G Q P F S L H H P S R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520554 1130 130719 Q392 F P L S R P F Q L G N Y C N F
Chicken Gallus gallus
Frog Xenopus laevis Q641G3 1157 132483 Q419 F P I S R P F Q L G N Y S N F
Zebra Danio Brachydanio rerio XP_692597 792 87493 I223 R R Y P H L H I P S S L F H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393382 1157 132996 A365 F P P H M P F A L N K P C S F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780607 1183 135384 S394 F P I H R P M S V A Q P C T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.6 93 93.5 N.A. 91.4 91.3 N.A. 30.6 N.A. 30.5 27.6 N.A. N.A. 25.5 N.A. 26.3
Protein Similarity: 100 79.9 93.5 95.5 N.A. 94.4 94.6 N.A. 47.5 N.A. 47.1 44.2 N.A. N.A. 43.8 N.A. 43.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 46.6 N.A. 46.6 0 N.A. N.A. 40 N.A. 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 60 N.A. 66.6 6.6 N.A. N.A. 53.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 91 0 0 0 0 0 82 0 0 0 0 0 10 0 28 % F
% Gly: 0 0 0 19 0 0 0 0 0 19 0 0 0 0 0 % G
% His: 0 0 0 19 10 0 10 0 0 55 46 0 0 10 0 % H
% Ile: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 55 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 64 0 0 10 0 0 82 0 0 10 0 0 19 % L
% Met: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 19 0 0 19 0 % N
% Pro: 0 91 10 10 0 91 0 0 10 0 10 73 0 0 0 % P
% Gln: 0 0 0 0 55 0 0 19 0 0 10 0 0 0 0 % Q
% Arg: 10 10 0 0 28 0 0 0 0 0 0 0 0 55 0 % R
% Ser: 0 0 0 55 0 0 0 64 0 10 10 0 64 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 19 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _