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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM58A
All Species:
35.15
Human Site:
T164
Identified Species:
70.3
UniProt:
Q8N1B3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1B3
NP_001124469.1
248
28369
T164
N
R
H
S
W
Q
R
T
P
V
A
V
T
A
W
Chimpanzee
Pan troglodytes
XP_001137614
206
24109
V126
W
Q
R
T
P
V
A
V
T
A
W
A
L
L
R
Rhesus Macaque
Macaca mulatta
XP_001083983
248
28309
T164
N
R
H
S
W
Q
R
T
P
V
A
V
T
A
W
Dog
Lupus familis
XP_549359
333
37928
T249
N
R
Y
S
W
Q
R
T
P
V
S
V
T
A
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR8
250
28910
T166
N
R
Y
S
W
Q
R
T
P
I
S
V
T
A
W
Rat
Rattus norvegicus
Q4QQW5
250
28929
T166
N
R
Y
S
W
Q
R
T
P
I
S
V
T
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510926
282
32159
T198
N
R
H
S
W
E
R
T
P
I
S
V
A
A
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRK9
244
28393
T160
N
R
H
S
W
E
R
T
P
I
A
T
A
A
W
Zebra Danio
Brachydanio rerio
Q503D6
247
28422
T166
N
R
H
A
W
S
R
T
P
I
A
E
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25008
267
31274
R178
Q
L
L
T
L
S
W
R
I
V
N
D
S
L
R
Honey Bee
Apis mellifera
XP_395803
270
31164
Y183
G
E
E
E
W
S
K
Y
P
V
A
K
T
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797502
242
28381
T159
D
R
D
V
W
D
Q
T
P
V
C
R
T
A
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
98.7
63.9
N.A.
88.4
87.1
N.A.
68.7
N.A.
68.9
59.6
N.A.
22.4
38.5
N.A.
49.6
Protein Similarity:
100
83
99.5
69.3
N.A.
93.1
92.4
N.A.
79
N.A.
81.4
76.6
N.A.
38.5
55.5
N.A.
70.5
P-Site Identity:
100
0
100
86.6
N.A.
80
80
N.A.
73.3
N.A.
73.3
66.6
N.A.
6.6
33.3
N.A.
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
20
46.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
0
9
42
9
17
75
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
9
9
9
0
17
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
42
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% K
% Leu:
0
9
9
0
9
0
0
0
0
0
0
0
9
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
67
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
84
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
42
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
75
9
0
0
0
67
9
0
0
0
9
0
0
17
% R
% Ser:
0
0
0
59
0
25
0
0
0
0
34
0
9
9
0
% S
% Thr:
0
0
0
17
0
0
0
75
9
0
0
9
67
0
0
% T
% Val:
0
0
0
9
0
9
0
9
0
50
0
50
0
0
0
% V
% Trp:
9
0
0
0
84
0
9
0
0
0
9
0
0
0
67
% W
% Tyr:
0
0
25
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _