KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM58A
All Species:
40
Human Site:
Y144
Identified Species:
80
UniProt:
Q8N1B3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1B3
NP_001124469.1
248
28369
Y144
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
V
S
Chimpanzee
Pan troglodytes
XP_001137614
206
24109
Y106
P
H
K
Y
L
L
H
Y
L
V
S
L
Q
N
W
Rhesus Macaque
Macaca mulatta
XP_001083983
248
28309
Y144
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
V
S
Dog
Lupus familis
XP_549359
333
37928
Y229
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR8
250
28910
Y146
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
I
S
Rat
Rattus norvegicus
Q4QQW5
250
28929
Y146
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510926
282
32159
Y178
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
I
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRK9
244
28393
Y140
S
F
Q
H
P
H
K
Y
L
L
H
Y
L
I
S
Zebra Danio
Brachydanio rerio
Q503D6
247
28422
Y146
T
F
E
H
P
H
K
Y
L
L
H
Y
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25008
267
31274
P158
I
V
Y
Q
P
Y
R
P
L
L
Q
L
V
Q
D
Honey Bee
Apis mellifera
XP_395803
270
31164
Y163
T
P
I
H
P
H
K
Y
M
L
H
Y
L
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797502
242
28381
Y139
I
G
D
L
P
H
K
Y
L
V
H
Y
L
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
98.7
63.9
N.A.
88.4
87.1
N.A.
68.7
N.A.
68.9
59.6
N.A.
22.4
38.5
N.A.
49.6
Protein Similarity:
100
83
99.5
69.3
N.A.
93.1
92.4
N.A.
79
N.A.
81.4
76.6
N.A.
38.5
55.5
N.A.
70.5
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
93.3
80
N.A.
20
66.6
N.A.
60
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
40
80
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
75
0
84
9
0
0
0
84
0
0
0
0
% H
% Ile:
17
0
9
0
0
0
0
0
0
0
0
0
0
42
0
% I
% Lys:
0
0
9
0
0
0
84
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
9
9
9
0
0
92
84
0
17
84
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
9
0
0
92
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
59
9
0
0
0
0
0
0
9
0
9
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% R
% Ser:
59
0
0
0
0
0
0
0
0
0
9
0
0
0
84
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
17
0
0
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
9
9
0
9
0
92
0
0
0
84
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _