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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM58A All Species: 39.39
Human Site: Y148 Identified Species: 78.79
UniProt: Q8N1B3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N1B3 NP_001124469.1 248 28369 Y148 P H K Y L L H Y L V S L Q N W
Chimpanzee Pan troglodytes XP_001137614 206 24109 L110 L L H Y L V S L Q N W L N R H
Rhesus Macaque Macaca mulatta XP_001083983 248 28309 Y148 P H K Y L L H Y L V S L K N W
Dog Lupus familis XP_549359 333 37928 Y233 P H K Y L L H Y L I S L K N W
Cat Felis silvestris
Mouse Mus musculus Q8QZR8 250 28910 Y150 P H K Y L L H Y L I S L K N W
Rat Rattus norvegicus Q4QQW5 250 28929 Y150 P H K Y L L H Y L I S L K N W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510926 282 32159 Y182 P H K Y L L H Y L I S L K H W
Chicken Gallus gallus
Frog Xenopus laevis Q6NRK9 244 28393 Y144 P H K Y L L H Y L I S L K N W
Zebra Danio Brachydanio rerio Q503D6 247 28422 Y150 P H K Y L L H Y L L S V R S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25008 267 31274 L162 P Y R P L L Q L V Q D M G Q E
Honey Bee Apis mellifera XP_395803 270 31164 Y167 P H K Y M L H Y L R S L Q A W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797502 242 28381 Y143 P H K Y L V H Y L K S L S H W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 98.7 63.9 N.A. 88.4 87.1 N.A. 68.7 N.A. 68.9 59.6 N.A. 22.4 38.5 N.A. 49.6
Protein Similarity: 100 83 99.5 69.3 N.A. 93.1 92.4 N.A. 79 N.A. 81.4 76.6 N.A. 38.5 55.5 N.A. 70.5
P-Site Identity: 100 20 93.3 86.6 N.A. 86.6 86.6 N.A. 80 N.A. 86.6 66.6 N.A. 20 80 N.A. 73.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 N.A. 100 93.3 N.A. 46.6 86.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 84 9 0 0 0 84 0 0 0 0 0 0 17 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % I
% Lys: 0 0 84 0 0 0 0 0 0 9 0 0 50 0 0 % K
% Leu: 9 9 0 0 92 84 0 17 84 9 0 84 0 0 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 9 50 0 % N
% Pro: 92 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 9 9 0 0 17 9 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 9 0 0 9 9 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 0 84 0 9 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 17 0 0 9 17 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 75 % W
% Tyr: 0 9 0 92 0 0 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _