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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS52
All Species:
26.67
Human Site:
T146
Identified Species:
65.19
UniProt:
Q8N1B4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1B4
NP_072047.4
723
82221
T146
S
I
S
S
E
I
R
T
L
Q
E
Q
S
G
A
Chimpanzee
Pan troglodytes
XP_001169608
721
81977
T146
S
I
S
S
E
I
R
T
L
Q
E
Q
S
G
A
Rhesus Macaque
Macaca mulatta
XP_001116041
723
82197
T146
S
I
S
S
E
I
R
T
L
Q
E
Q
S
G
A
Dog
Lupus familis
XP_851715
655
74715
T133
S
I
S
S
E
I
R
T
L
Q
E
Q
S
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C754
723
82026
T146
S
I
S
S
E
I
R
T
L
Q
E
Q
S
G
A
Rat
Rattus norvegicus
O55166
723
82085
T146
S
I
S
C
E
I
R
T
L
Q
E
Q
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684689
724
82832
T147
S
I
S
S
E
I
Q
T
L
Q
Q
Q
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608931
662
77414
F119
V
K
A
Q
L
S
Q
F
I
E
D
M
A
V
S
Honey Bee
Apis mellifera
XP_395807
667
77376
P121
N
R
Q
I
I
R
G
P
L
S
Q
F
I
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307938
718
81721
I133
S
I
S
S
D
I
K
I
L
Q
E
K
S
M
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
83.6
N.A.
98.1
98.3
N.A.
N.A.
N.A.
N.A.
72.6
N.A.
48.1
50.9
N.A.
N.A.
Protein Similarity:
100
99.3
99.5
86.4
N.A.
99.1
99.1
N.A.
N.A.
N.A.
N.A.
86.1
N.A.
69.2
71.7
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
46.6
20
N.A.
N.A.
Percent
Protein Identity:
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
60
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
20
% D
% Glu:
0
0
0
0
70
0
0
0
0
10
70
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
60
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
80
0
10
10
80
0
10
10
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
90
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
20
0
0
80
20
70
0
0
0
% Q
% Arg:
0
10
0
0
0
10
60
0
0
0
0
0
0
0
0
% R
% Ser:
80
0
80
70
0
10
0
0
0
10
0
0
80
0
20
% S
% Thr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _