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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS52
All Species:
30.61
Human Site:
T217
Identified Species:
74.81
UniProt:
Q8N1B4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1B4
NP_072047.4
723
82221
T217
R
E
Q
E
A
R
G
T
A
A
C
A
D
V
R
Chimpanzee
Pan troglodytes
XP_001169608
721
81977
T217
R
E
Q
E
A
R
G
T
A
A
C
A
D
V
R
Rhesus Macaque
Macaca mulatta
XP_001116041
723
82197
T217
R
E
Q
E
A
R
G
T
A
A
C
A
D
V
R
Dog
Lupus familis
XP_851715
655
74715
T204
R
E
Q
E
A
R
G
T
A
V
C
A
D
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C754
723
82026
T217
R
E
Q
E
A
M
G
T
A
A
C
A
D
V
R
Rat
Rattus norvegicus
O55166
723
82085
T217
R
E
Q
E
A
R
G
T
A
A
C
A
D
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684689
724
82832
T218
K
E
L
S
F
R
E
T
L
A
C
S
D
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608931
662
77414
T168
S
F
K
E
S
K
S
T
S
D
V
S
D
V
L
Honey Bee
Apis mellifera
XP_395807
667
77376
A171
K
E
Q
S
F
K
E
A
K
S
C
L
D
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307938
718
81721
S219
A
D
Q
L
I
K
G
S
K
A
L
K
D
V
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
83.6
N.A.
98.1
98.3
N.A.
N.A.
N.A.
N.A.
72.6
N.A.
48.1
50.9
N.A.
N.A.
Protein Similarity:
100
99.3
99.5
86.4
N.A.
99.1
99.1
N.A.
N.A.
N.A.
N.A.
86.1
N.A.
69.2
71.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
40
N.A.
26.6
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
60
60
N.A.
N.A.
Percent
Protein Identity:
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
60
0
0
10
60
70
0
60
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
0
0
100
0
0
% D
% Glu:
0
80
0
70
0
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
20
0
10
0
0
30
0
0
20
0
0
10
0
0
10
% K
% Leu:
0
0
10
10
0
0
0
0
10
0
10
10
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
20
% Q
% Arg:
60
0
0
0
0
60
0
0
0
0
0
0
0
0
60
% R
% Ser:
10
0
0
20
10
0
10
10
10
10
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
90
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _