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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS52 All Species: 24.85
Human Site: T504 Identified Species: 60.74
UniProt: Q8N1B4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N1B4 NP_072047.4 723 82221 T504 Q R L G G L D T R P H Y I T R
Chimpanzee Pan troglodytes XP_001169608 721 81977 T502 Q R L G G L D T R P H Y I T R
Rhesus Macaque Macaca mulatta XP_001116041 723 82197 T504 Q R L G G L D T R P H Y I T R
Dog Lupus familis XP_851715 655 74715 F478 L Q V E V E N F V L Q V A A E
Cat Felis silvestris
Mouse Mus musculus Q8C754 723 82026 T504 Q R L G G L D T R P H Y I T R
Rat Rattus norvegicus O55166 723 82085 T504 Q R L G G L D T R P H Y I T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684689 724 82832 T505 Q K L G V L D T R P H Y I T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608931 662 77414 L449 P T K F N K E L G P H Y I T R
Honey Bee Apis mellifera XP_395807 667 77376 T454 P L K L T Q E T G P H Y I T R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307938 718 81721 V501 K T L W E D D V H P H Y V M R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.3 83.6 N.A. 98.1 98.3 N.A. N.A. N.A. N.A. 72.6 N.A. 48.1 50.9 N.A. N.A.
Protein Similarity: 100 99.3 99.5 86.4 N.A. 99.1 99.1 N.A. N.A. N.A. N.A. 86.1 N.A. 69.2 71.7 N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. N.A. N.A. N.A. 86.6 N.A. 40 46.6 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. N.A. N.A. N.A. 93.3 N.A. 46.6 53.3 N.A. N.A.
Percent
Protein Identity: 35.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 60.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 53.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 70 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 10 20 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 60 50 0 0 0 20 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 90 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % I
% Lys: 10 10 20 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 70 10 0 60 0 10 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 20 0 0 0 0 0 0 0 0 90 0 0 0 0 0 % P
% Gln: 60 10 0 0 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 50 0 0 0 0 0 0 60 0 0 0 0 0 90 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 20 0 0 10 0 0 70 0 0 0 0 0 80 0 % T
% Val: 0 0 10 0 20 0 0 10 10 0 0 10 10 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _