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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS52
All Species:
27.27
Human Site:
Y433
Identified Species:
66.67
UniProt:
Q8N1B4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1B4
NP_072047.4
723
82221
Y433
T
L
K
H
L
D
S
Y
L
A
D
C
Y
D
A
Chimpanzee
Pan troglodytes
XP_001169608
721
81977
Y431
T
L
K
H
L
D
S
Y
L
A
D
C
Y
D
A
Rhesus Macaque
Macaca mulatta
XP_001116041
723
82197
Y433
T
L
K
H
L
E
S
Y
L
A
D
C
Y
D
A
Dog
Lupus familis
XP_851715
655
74715
Y420
T
L
K
H
L
E
S
Y
L
T
D
C
Y
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C754
723
82026
Y433
T
L
K
H
L
E
S
Y
L
A
D
C
Y
D
A
Rat
Rattus norvegicus
O55166
723
82085
Y433
T
L
K
H
L
E
S
Y
L
A
D
C
Y
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684689
724
82832
Y434
F
L
K
N
L
S
T
Y
L
S
D
C
Y
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608931
662
77414
H381
K
N
L
E
T
S
I
H
D
C
F
D
T
I
A
Honey Bee
Apis mellifera
XP_395807
667
77376
D387
N
L
Q
S
F
V
E
D
C
Y
D
T
I
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307938
718
81721
Y435
N
S
I
L
P
N
C
Y
D
A
I
G
L
M
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
83.6
N.A.
98.1
98.3
N.A.
N.A.
N.A.
N.A.
72.6
N.A.
48.1
50.9
N.A.
N.A.
Protein Similarity:
100
99.3
99.5
86.4
N.A.
99.1
99.1
N.A.
N.A.
N.A.
N.A.
86.1
N.A.
69.2
71.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
60
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
60
0
0
0
10
70
% A
% Cys:
0
0
0
0
0
0
10
0
10
10
0
70
0
0
0
% C
% Asp:
0
0
0
0
0
20
0
10
20
0
80
10
0
70
0
% D
% Glu:
0
0
0
10
0
40
10
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
60
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
10
0
10
10
0
% I
% Lys:
10
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
80
10
10
70
0
0
0
70
0
0
0
10
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
20
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
10
0
20
60
0
0
10
0
0
0
0
10
% S
% Thr:
60
0
0
0
10
0
10
0
0
10
0
10
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
10
0
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _