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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THEMIS
All Species:
7.88
Human Site:
S584
Identified Species:
21.67
UniProt:
Q8N1K5
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1K5
NP_001010923.1
641
73452
S584
R
T
V
D
L
P
K
S
P
K
R
H
H
V
D
Chimpanzee
Pan troglodytes
XP_518734
641
73457
S584
R
T
V
D
L
P
K
S
P
K
R
H
H
V
D
Rhesus Macaque
Macaca mulatta
XP_001112611
644
72320
G580
V
K
S
S
Q
V
L
G
L
Q
Q
H
A
L
L
Dog
Lupus familis
XP_541237
645
73268
K589
D
R
A
V
G
L
P
K
S
P
K
S
L
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW0
636
72762
T580
L
S
L
A
E
E
R
T
I
N
L
P
K
S
L
Rat
Rattus norvegicus
XP_575925
657
73351
C582
V
V
E
P
K
P
S
C
P
Q
L
E
R
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509271
594
67325
E538
M
V
E
E
I
S
E
E
Q
Y
Y
M
V
R
R
Chicken
Gallus gallus
XP_001232459
752
86042
P584
V
S
G
V
L
Q
A
P
K
N
F
C
V
D
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PF62
675
76607
S577
N
S
E
S
S
S
C
S
P
K
T
L
H
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
32.7
86.5
N.A.
79.2
32.2
N.A.
64.1
55.1
N.A.
36.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
52.3
90.3
N.A.
87.9
53.5
N.A.
76.1
67.8
N.A.
57.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
0
13.3
N.A.
0
6.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
26.6
20
N.A.
20
13.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
12
0
0
0
0
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
12
12
0
0
0
12
0
0
0
% C
% Asp:
12
0
0
23
0
0
0
0
0
0
0
0
0
12
23
% D
% Glu:
0
0
34
12
12
12
12
12
0
0
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
12
0
12
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
34
34
12
0
% H
% Ile:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
12
0
23
12
12
34
12
0
12
12
0
% K
% Leu:
12
0
12
0
34
12
12
0
12
0
23
12
12
12
23
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
34
12
12
45
12
0
12
0
0
0
% P
% Gln:
0
0
0
0
12
12
0
0
12
23
12
0
0
0
0
% Q
% Arg:
23
12
0
0
0
0
12
0
0
0
23
0
12
12
12
% R
% Ser:
0
34
12
23
12
23
12
34
12
0
0
12
0
12
0
% S
% Thr:
0
23
0
0
0
0
0
12
0
0
12
0
0
0
12
% T
% Val:
34
23
23
23
0
12
0
0
0
0
0
0
23
34
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _