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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THEM5
All Species:
8.48
Human Site:
S61
Identified Species:
20.74
UniProt:
Q8N1Q8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1Q8
NP_872384.1
247
27677
S61
D
Y
A
L
P
N
A
S
W
C
S
D
M
L
S
Chimpanzee
Pan troglodytes
XP_513806
240
27259
K55
V
P
N
P
S
W
N
K
D
L
R
L
L
F
D
Rhesus Macaque
Macaca mulatta
XP_001108917
116
12553
Dog
Lupus familis
XP_850889
247
27608
S61
D
Y
A
L
P
N
A
S
W
C
P
D
M
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ0
248
27846
S61
D
Y
A
L
P
N
A
S
W
C
S
D
M
L
S
Rat
Rattus norvegicus
Q566R0
230
26071
K46
L
P
N
P
S
W
T
K
D
L
R
L
L
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520286
141
15507
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GLK2
222
24962
Q37
T
A
P
K
F
Y
S
Q
E
A
P
R
D
Y
G
Zebra Danio
Brachydanio rerio
NP_001074103
222
24562
M37
N
P
S
W
S
P
E
M
R
K
F
Y
D
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188893
199
21898
R16
N
P
K
S
T
S
E
R
D
L
P
G
W
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.2
22.6
82.5
N.A.
77.8
35.2
N.A.
34
N.A.
34.8
30.3
N.A.
N.A.
N.A.
N.A.
25.9
Protein Similarity:
100
58.7
35.2
89.4
N.A.
88.7
56.2
N.A.
46.1
N.A.
58.7
48.9
N.A.
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
0
0
86.6
N.A.
100
0
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
0
86.6
N.A.
100
6.6
N.A.
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
0
0
0
30
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% C
% Asp:
30
0
0
0
0
0
0
0
30
0
0
30
20
0
30
% D
% Glu:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
10
0
0
20
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
20
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
30
0
0
0
0
0
30
0
20
20
30
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
30
0
0
% M
% Asn:
20
0
20
0
0
30
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
40
10
20
30
10
0
0
0
0
30
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
20
10
0
0
0
% R
% Ser:
0
0
10
10
30
10
10
30
0
0
20
0
0
0
20
% S
% Thr:
10
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
20
0
0
30
0
0
0
10
0
0
% W
% Tyr:
0
30
0
0
0
10
0
0
0
0
0
10
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _