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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RGNEF All Species: 13.94
Human Site: S535 Identified Species: 38.33
UniProt: Q8N1W1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N1W1 NP_001171164 1705 191892 S535 F N I S R A E S L P L S S N L
Chimpanzee Pan troglodytes XP_001151367 1705 191784 S535 F N I S R A E S L P L S S N L
Rhesus Macaque Macaca mulatta XP_001101425 1652 185793 S535 F N I S R A E S L P L S S N L
Dog Lupus familis XP_544372 1164 129679 G104 H F L L C L P G G V Q A L S L
Cat Felis silvestris
Mouse Mus musculus P97433 1693 190307 L535 N I S R T E S L S L S S T L H
Rat Rattus norvegicus P0C6P5 1700 190739 L535 N I S R T E S L S L S S T L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513315 1648 184528 S529 F N I S R T E S L S L S S N L
Chicken Gallus gallus XP_424789 1345 153050 I285 D S L G R P R I L Q D F T V G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688428 1378 155180 Y318 S F I K S R M Y S T R N K N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 93.3 54.2 N.A. 79.8 79 N.A. 64.6 47.9 N.A. 38.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 94.8 59.2 N.A. 86.5 85.9 N.A. 74.8 60.7 N.A. 52.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. 86.6 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 13.3 13.3 N.A. 86.6 33.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 34 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % D
% Glu: 0 0 0 0 0 23 45 0 0 0 0 0 0 0 0 % E
% Phe: 45 23 0 0 0 0 0 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 12 12 0 0 0 0 0 12 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % H
% Ile: 0 23 56 0 0 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 0 0 12 0 12 % K
% Leu: 0 0 23 12 0 12 0 23 56 23 45 0 12 23 56 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 23 45 0 0 0 0 0 0 0 0 0 12 0 56 0 % N
% Pro: 0 0 0 0 0 12 12 0 0 34 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 12 0 0 0 0 % Q
% Arg: 0 0 0 23 56 12 12 0 0 0 12 0 0 0 0 % R
% Ser: 12 12 23 45 12 0 23 45 34 12 23 67 45 12 0 % S
% Thr: 0 0 0 0 23 12 0 0 0 12 0 0 34 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 12 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _