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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C19orf46 All Species: 8.18
Human Site: S224 Identified Species: 30
UniProt: Q8N205 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N205 NP_001034965.1 404 43512 S224 D L E V E G D S D W P G P G G
Chimpanzee Pan troglodytes XP_001162212 404 43431 S224 D L E V E G D S D W P G P G G
Rhesus Macaque Macaca mulatta XP_001101040 404 43834 L224 D L E F E G D L D W P A R G G
Dog Lupus familis XP_855449 259 28333 W106 S I F R R L W W L Q A Q L V T
Cat Felis silvestris
Mouse Mus musculus Q8CII8 388 42005 S220 D L E V E G D S D G P A A G G
Rat Rattus norvegicus Q5M844 340 36496 G178 D S D G P A A G G V W G P W A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510248 212 22824 G58 L F D G E E E G A R L G L A E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 91.5 50.7 N.A. 66.3 57.6 N.A. 24.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.5 93.8 54.4 N.A. 74.7 64.8 N.A. 33.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 0 N.A. 80 20 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 6.6 N.A. 80 26.6 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 15 0 15 0 15 29 15 15 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 72 0 29 0 0 0 58 0 58 0 0 0 0 0 0 % D
% Glu: 0 0 58 0 72 15 15 0 0 0 0 0 0 0 15 % E
% Phe: 0 15 15 15 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 29 0 58 0 29 15 15 0 58 0 58 58 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 15 58 0 0 0 15 0 15 15 0 15 0 29 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 15 0 0 0 0 0 58 0 43 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 15 0 15 0 0 0 % Q
% Arg: 0 0 0 15 15 0 0 0 0 15 0 0 15 0 0 % R
% Ser: 15 15 0 0 0 0 0 43 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % T
% Val: 0 0 0 43 0 0 0 0 0 15 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 15 15 0 43 15 0 0 15 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _