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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCML4 All Species: 8.18
Human Site: S247 Identified Species: 25.71
UniProt: Q8N228 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N228 NP_932347.2 414 45023 S247 P V G M N R Y S V D T S A S T
Chimpanzee Pan troglodytes B0FZN7 329 37334 C188 P V H P S D F C E H N Y Q S Y
Rhesus Macaque Macaca mulatta B0FZP2 329 37512 S188 P V H P S D F S E H N Y Q P Y
Dog Lupus familis XP_539072 414 44824 S247 P V G M N R Y S V D P S A S A
Cat Felis silvestris
Mouse Mus musculus Q80VG1 408 44427 A247 A V G M N R Y A M D F S H R G
Rat Rattus norvegicus Q9JMD2 863 97487 S655 P G G H S N L S C A L K K T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426184 406 44209 A247 A N M K R Y S A D P T D S A F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q8QHL5 827 88661 T468 Q N V P D K D T P V L L E P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.6 22.9 91 N.A. 78.9 20.2 N.A. N.A. 69.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.5 41.2 93.4 N.A. 86.4 30.4 N.A. N.A. 79.7 N.A. 30.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 20 86.6 N.A. 53.3 20 N.A. N.A. 6.6 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 33.3 86.6 N.A. 66.6 40 N.A. N.A. 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 0 0 0 0 25 0 13 0 0 25 13 13 % A
% Cys: 0 0 0 0 0 0 0 13 13 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 25 13 0 13 38 0 13 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 25 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 25 0 0 0 13 0 0 0 13 % F
% Gly: 0 13 50 0 0 0 0 0 0 0 0 0 0 0 13 % G
% His: 0 0 25 13 0 0 0 0 0 25 0 0 13 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 13 0 13 0 0 0 0 0 13 13 0 0 % K
% Leu: 0 0 0 0 0 0 13 0 0 0 25 13 0 0 0 % L
% Met: 0 0 13 38 0 0 0 0 13 0 0 0 0 0 0 % M
% Asn: 0 25 0 0 38 13 0 0 0 0 25 0 0 0 0 % N
% Pro: 63 0 0 38 0 0 0 0 13 13 13 0 0 25 0 % P
% Gln: 13 0 0 0 0 0 0 0 0 0 0 0 25 0 13 % Q
% Arg: 0 0 0 0 13 38 0 0 0 0 0 0 0 13 0 % R
% Ser: 0 0 0 0 38 0 13 50 0 0 0 38 13 38 13 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 25 0 0 13 13 % T
% Val: 0 63 13 0 0 0 0 0 25 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 38 0 0 0 0 25 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _