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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROM2
All Species:
23.03
Human Site:
Y421
Identified Species:
56.3
UniProt:
Q8N271
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N271
NP_653308.1
834
91883
Y421
Y
L
Q
E
V
Q
R
Y
E
T
Y
R
W
I
V
Chimpanzee
Pan troglodytes
XP_001143498
834
91723
Y421
Y
L
Q
E
V
Q
R
Y
E
T
Y
R
W
I
V
Rhesus Macaque
Macaca mulatta
XP_001095857
840
91577
Y421
Y
L
Q
E
V
Q
R
Y
E
T
Y
R
W
I
V
Dog
Lupus familis
XP_854455
837
92260
Y424
Y
L
K
E
V
Q
R
Y
E
K
Y
R
W
I
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3UUY6
835
93187
Y422
Y
L
Q
E
V
Q
Q
Y
E
T
Y
R
W
I
L
Rat
Rattus norvegicus
Q8CJ52
834
92822
Y421
Y
L
Q
D
V
Q
R
Y
E
T
Y
R
W
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509143
526
56793
G149
Q
L
N
P
F
P
A
G
L
V
R
T
A
L
N
Chicken
Gallus gallus
XP_425759
548
61778
W171
Q
T
L
V
C
R
N
W
V
N
Q
E
I
Y
K
Frog
Xenopus laevis
NP_001163922
757
85473
T377
S
K
S
I
S
E
T
T
Q
A
L
D
T
I
E
Zebra Danio
Brachydanio rerio
Q9W735
826
91929
M426
I
Y
P
Q
I
D
Q
M
D
F
Y
R
W
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
90
79
N.A.
73.1
75
N.A.
33.3
24.7
29.9
28.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
93.5
87.2
N.A.
84.1
85.3
N.A.
42.3
39.6
48.5
49.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
6.6
0
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
13.3
13.3
20
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
0
50
0
10
0
0
60
0
0
10
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
10
0
0
0
0
0
0
0
10
80
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
10
0
0
0
0
10
% K
% Leu:
0
70
10
0
0
0
0
0
10
0
10
0
0
10
20
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
10
0
0
0
0
10
% N
% Pro:
0
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
20
0
50
10
0
60
20
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
50
0
0
0
10
70
0
0
0
% R
% Ser:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
10
0
50
0
10
10
0
0
% T
% Val:
0
0
0
10
60
0
0
0
10
10
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
70
0
10
% W
% Tyr:
60
10
0
0
0
0
0
60
0
0
70
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _