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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD6
All Species:
4.24
Human Site:
S225
Identified Species:
10.37
UniProt:
Q8N2A8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2A8
NP_849158.1
252
28273
S225
P
P
K
K
S
H
G
S
C
A
P
P
V
S
R
Chimpanzee
Pan troglodytes
XP_511307
252
28343
S225
P
Q
K
K
S
H
G
S
C
A
P
P
V
S
R
Rhesus Macaque
Macaca mulatta
XP_001092274
224
25415
F198
D
D
E
Y
V
R
L
F
L
E
E
F
E
R
I
Dog
Lupus familis
XP_546664
228
25876
F202
D
E
E
Y
V
R
L
F
L
E
E
F
E
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWZ9
221
25023
F195
D
T
E
Y
V
R
L
F
L
E
E
F
E
R
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510999
199
22292
N173
W
E
E
Y
N
P
A
N
Y
T
F
F
S
Q
E
Chicken
Gallus gallus
XP_001233655
79
9318
A53
N
V
V
I
M
E
D
A
E
Y
V
R
P
F
L
Frog
Xenopus laevis
A1L1C2
210
23900
A184
D
D
T
V
I
V
K
A
Y
Q
K
E
F
E
R
Zebra Danio
Brachydanio rerio
A3KNW0
227
25838
F200
E
P
E
L
V
R
P
F
Q
Q
E
F
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609530
253
28501
L227
I
I
T
A
D
D
K
L
T
A
T
F
Q
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
84.1
76.9
N.A.
74.5
N.A.
N.A.
38.4
23.8
49.5
44.8
N.A.
22.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
85.7
80.9
N.A.
80.5
N.A.
N.A.
49.2
27.7
64.6
61.5
N.A.
43.4
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
0
N.A.
0
N.A.
N.A.
0
0
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
20
6.6
13.3
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
20
0
30
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% C
% Asp:
40
20
0
0
10
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
20
50
0
0
10
0
0
10
30
40
10
30
10
20
% E
% Phe:
0
0
0
0
0
0
0
40
0
0
10
60
10
10
0
% F
% Gly:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
10
10
0
0
0
0
0
0
0
0
0
30
% I
% Lys:
0
0
20
20
0
0
20
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
30
10
30
0
0
0
10
0
20
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
20
20
0
0
0
10
10
0
0
0
20
20
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
20
0
0
10
10
0
% Q
% Arg:
0
0
0
0
0
40
0
0
0
0
0
10
0
30
30
% R
% Ser:
0
0
0
0
20
0
0
20
0
0
0
0
10
20
0
% S
% Thr:
0
10
20
0
0
0
0
0
10
10
10
0
0
0
0
% T
% Val:
0
10
10
10
40
10
0
0
0
0
10
0
20
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
0
0
0
20
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _