KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GHDC
All Species:
5.15
Human Site:
T179
Identified Species:
12.59
UniProt:
Q8N2G8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2G8
NP_001136094.1
530
57523
T179
G
Q
V
G
T
P
G
T
K
D
P
R
A
L
L
Chimpanzee
Pan troglodytes
XP_001166343
530
57648
T179
G
Q
M
G
T
P
G
T
K
D
P
R
A
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849480
529
57233
A183
G
Q
V
S
T
P
G
A
K
H
P
G
T
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99J23
532
58473
A180
G
R
V
S
P
D
G
A
K
D
P
R
T
L
L
Rat
Rattus norvegicus
XP_220981
527
57849
A178
G
R
V
S
P
I
G
A
K
D
A
R
T
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418150
304
33827
R32
R
G
S
G
G
M
V
R
G
P
C
P
Q
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795021
622
70275
R238
A
F
D
I
T
T
E
R
E
A
L
Y
A
H
L
Poplar Tree
Populus trichocarpa
XP_002319398
608
68779
Y178
T
S
Y
Y
K
S
S
Y
F
R
D
R
P
Y
D
Maize
Zea mays
NP_001146837
610
66901
Q222
I
L
C
A
D
A
F
Q
S
M
Y
A
Q
M
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQ68
597
67028
S186
K
S
D
Y
F
R
T
S
D
S
D
S
V
Y
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
N.A.
82.8
N.A.
73.5
74.1
N.A.
N.A.
31.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
99.2
N.A.
86.7
N.A.
81.3
81.1
N.A.
N.A.
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.6
P-Site Identity:
100
93.3
N.A.
66.6
N.A.
60
53.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
66.6
N.A.
66.6
60
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
22.2
26
N.A.
21.2
N.A.
N.A.
Protein Similarity:
39.6
41.3
N.A.
40.2
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
10
0
30
0
10
10
10
30
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
20
0
10
10
0
0
10
40
20
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
10
0
10
0
10
0
0
0
0
0
0
% F
% Gly:
50
10
0
30
10
0
50
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
50
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
10
0
0
60
60
% L
% Met:
0
0
10
0
0
10
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
30
0
0
0
10
40
10
10
0
10
% P
% Gln:
0
30
0
0
0
0
0
10
0
0
0
0
20
0
0
% Q
% Arg:
10
20
0
0
0
10
0
20
0
10
0
50
0
0
0
% R
% Ser:
0
20
10
30
0
10
10
10
10
10
0
10
0
0
0
% S
% Thr:
10
0
0
0
40
10
10
20
0
0
0
0
30
0
10
% T
% Val:
0
0
40
0
0
0
10
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
20
0
0
0
10
0
0
10
10
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _