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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GHDC
All Species:
29.7
Human Site:
Y349
Identified Species:
72.59
UniProt:
Q8N2G8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2G8
NP_001136094.1
530
57523
Y349
E
A
Q
Q
G
K
E
Y
E
L
V
L
T
D
R
Chimpanzee
Pan troglodytes
XP_001166343
530
57648
Y349
E
A
Q
Q
G
K
E
Y
E
L
V
L
T
D
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849480
529
57233
Y348
E
A
Q
K
G
E
E
Y
E
L
V
L
T
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q99J23
532
58473
Y350
D
A
Q
R
E
K
E
Y
E
L
V
L
T
N
H
Rat
Rattus norvegicus
XP_220981
527
57849
Y347
D
V
R
R
E
E
K
Y
E
L
V
L
T
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418150
304
33827
H153
V
L
R
V
A
G
F
H
K
Q
C
P
V
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795021
622
70275
Y424
Q
V
E
K
G
A
T
Y
E
L
V
L
T
N
M
Poplar Tree
Populus trichocarpa
XP_002319398
608
68779
Y405
D
V
K
L
G
E
E
Y
E
L
V
V
T
T
Y
Maize
Zea mays
NP_001146837
610
66901
Y408
R
V
E
R
G
R
E
Y
E
L
V
I
T
T
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQ68
597
67028
Y397
D
V
E
V
G
K
E
Y
E
L
V
I
T
T
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
N.A.
82.8
N.A.
73.5
74.1
N.A.
N.A.
31.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
99.2
N.A.
86.7
N.A.
81.3
81.1
N.A.
N.A.
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.6
P-Site Identity:
100
100
N.A.
73.3
N.A.
66.6
46.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
22.2
26
N.A.
21.2
N.A.
N.A.
Protein Similarity:
39.6
41.3
N.A.
40.2
N.A.
N.A.
P-Site Identity:
46.6
46.6
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
73.3
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
10
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
40
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% D
% Glu:
30
0
30
0
20
30
70
0
90
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
70
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
10
20
0
40
10
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
10
0
0
0
0
0
90
0
60
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
40
20
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
20
30
0
10
0
0
0
0
0
0
0
0
20
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
90
30
0
% T
% Val:
10
50
0
20
0
0
0
0
0
0
90
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
30
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _