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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYROXD2 All Species: 27.58
Human Site: S429 Identified Species: 67.41
UniProt: Q8N2H3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N2H3 NP_116098.2 581 63068 S429 D A M D G L P S H R P V I E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105930 581 62770 S429 D A M D G L P S H R P M I E L
Dog Lupus familis XP_534984 937 101613 S728 D A M D G L P S H R P M I E L
Cat Felis silvestris
Mouse Mus musculus Q3U4I7 580 62666 S428 D A K G G L P S Q K P M I E L
Rat Rattus norvegicus Q68FT3 581 62861 S429 D A K G G L P S Q R P M I E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423118 593 64444 S437 E A A H G H P S S R P M I E L
Frog Xenopus laevis NP_001088589 574 62793 S424 D A N R G I P S T R P M I E L
Zebra Danio Brachydanio rerio XP_002664259 352 37788 A218 S V L D P T L A P P G C H V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500428 544 60408 V399 G R Y S R R P V I E M T I P S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002310805 563 60894 S411 D A V N G V P S R R P V I E M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.8 52.4 N.A. 84.1 86 N.A. N.A. 70.4 69.1 37.8 N.A. N.A. N.A. 51.4 N.A.
Protein Similarity: 100 N.A. 98.1 56.8 N.A. 90.3 92 N.A. N.A. 80.2 81 46.8 N.A. N.A. N.A. 66.2 N.A.
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 66.6 73.3 N.A. N.A. 60 66.6 6.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 80 80 N.A. N.A. 73.3 80 26.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: 50.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 64.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 93.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 80 10 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 70 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 10 0 0 0 80 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 20 80 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 10 0 10 0 0 30 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 10 0 0 0 90 0 0 % I
% Lys: 0 0 20 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 50 10 0 0 0 0 0 0 0 70 % L
% Met: 0 0 30 0 0 0 0 0 0 0 10 60 0 0 10 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 90 0 10 10 80 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % Q
% Arg: 0 10 0 10 10 10 0 0 10 70 0 0 0 0 0 % R
% Ser: 10 0 0 10 0 0 0 80 10 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % T
% Val: 0 10 10 0 0 10 0 10 0 0 0 20 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _