KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD2
All Species:
27.58
Human Site:
S540
Identified Species:
67.41
UniProt:
Q8N2H3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2H3
NP_116098.2
581
63068
S540
A
R
P
V
P
L
H
S
G
Y
R
C
P
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105930
581
62770
S540
A
R
P
V
P
L
H
S
G
Y
R
C
P
L
Q
Dog
Lupus familis
XP_534984
937
101613
S839
A
R
P
T
P
L
H
S
G
Y
R
C
P
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3U4I7
580
62666
S539
A
R
P
V
P
Q
H
S
D
Y
R
C
P
V
Q
Rat
Rattus norvegicus
Q68FT3
581
62861
S540
A
R
P
V
P
Q
H
S
D
Y
R
C
P
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423118
593
64444
S548
T
R
P
A
P
S
Y
S
T
Y
Q
S
P
V
P
Frog
Xenopus laevis
NP_001088589
574
62793
S535
S
R
P
V
A
T
F
S
N
Y
K
T
P
I
P
Zebra Danio
Brachydanio rerio
XP_002664259
352
37788
C323
P
V
K
G
L
Y
L
C
G
S
G
S
H
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500428
544
60408
S506
S
R
P
I
S
K
W
S
N
Y
S
T
P
I
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310805
563
60894
S522
M
R
P
V
K
G
W
S
S
Y
R
T
P
L
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
52.4
N.A.
84.1
86
N.A.
N.A.
70.4
69.1
37.8
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
100
N.A.
98.1
56.8
N.A.
90.3
92
N.A.
N.A.
80.2
81
46.8
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
80
N.A.
N.A.
40
40
6.6
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
60
6.6
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
50.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
50
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
40
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
50
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
20
0
% I
% Lys:
0
0
10
0
10
10
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
10
30
10
0
0
0
0
0
0
40
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% N
% Pro:
10
0
90
0
60
0
0
0
0
0
0
0
90
10
20
% P
% Gln:
0
0
0
0
0
20
0
0
0
0
10
0
0
0
50
% Q
% Arg:
0
90
0
0
0
0
0
0
0
0
60
0
0
0
10
% R
% Ser:
20
0
0
0
10
10
0
90
10
10
10
20
0
0
0
% S
% Thr:
10
0
0
10
0
10
0
0
10
0
0
30
0
0
0
% T
% Val:
0
10
0
60
0
0
0
0
0
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
90
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _