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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD2
All Species:
29.7
Human Site:
T258
Identified Species:
72.59
UniProt:
Q8N2H3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2H3
NP_116098.2
581
63068
T258
G
A
M
T
S
P
H
T
P
G
S
G
Y
V
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105930
581
62770
T258
G
A
M
T
S
P
R
T
P
G
S
G
Y
V
L
Dog
Lupus familis
XP_534984
937
101613
T557
G
A
M
T
S
P
H
T
P
G
S
G
Y
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3U4I7
580
62666
T257
G
A
M
T
S
P
H
T
P
G
S
G
Y
V
L
Rat
Rattus norvegicus
Q68FT3
581
62861
T258
G
A
M
T
S
P
H
T
P
G
S
G
Y
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423118
593
64444
T266
G
A
M
S
S
P
H
T
P
G
G
G
Y
V
L
Frog
Xenopus laevis
NP_001088589
574
62793
T253
G
A
M
A
S
P
A
T
P
G
S
G
Y
V
L
Zebra Danio
Brachydanio rerio
XP_002664259
352
37788
G56
G
S
W
G
Y
V
E
G
G
M
G
G
V
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500428
544
60408
V237
G
Y
V
L
L
H
H
V
I
G
G
L
D
E
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310805
563
60894
T241
G
S
T
A
S
V
H
T
P
G
S
G
Y
V
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
52.4
N.A.
84.1
86
N.A.
N.A.
70.4
69.1
37.8
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
100
N.A.
98.1
56.8
N.A.
90.3
92
N.A.
N.A.
80.2
81
46.8
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
100
N.A.
93.3
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
50.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
20
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
100
0
0
10
0
0
0
10
10
90
30
90
0
0
0
% G
% His:
0
0
0
0
0
10
70
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
80
% L
% Met:
0
0
70
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
70
0
0
80
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
10
80
0
0
0
0
0
70
0
0
0
0
% S
% Thr:
0
0
10
50
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
20
0
10
0
0
0
0
10
80
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
0
0
0
80
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _