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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD2
All Species:
21.21
Human Site:
T331
Identified Species:
51.85
UniProt:
Q8N2H3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2H3
NP_116098.2
581
63068
T331
G
V
V
L
E
D
G
T
E
V
R
S
K
M
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105930
581
62770
T331
G
V
V
L
E
D
G
T
E
V
R
S
K
V
V
Dog
Lupus familis
XP_534984
937
101613
S630
G
V
V
L
Q
D
G
S
E
V
R
S
K
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U4I7
580
62666
E330
G
V
T
L
Q
D
G
E
E
V
R
S
R
V
V
Rat
Rattus norvegicus
Q68FT3
581
62861
E331
G
V
V
L
Q
G
G
E
E
V
R
S
R
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423118
593
64444
T339
G
V
V
M
Q
D
G
T
E
V
R
S
K
V
V
Frog
Xenopus laevis
NP_001088589
574
62793
T326
G
V
V
L
N
D
G
T
E
V
Q
S
S
L
V
Zebra Danio
Brachydanio rerio
XP_002664259
352
37788
Q125
T
F
K
R
L
T
P
Q
D
A
L
P
E
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500428
544
60408
M306
E
L
H
S
K
I
V
M
S
N
A
T
P
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310805
563
60894
T314
G
V
L
L
A
D
G
T
E
V
L
S
P
I
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
52.4
N.A.
84.1
86
N.A.
N.A.
70.4
69.1
37.8
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
100
N.A.
98.1
56.8
N.A.
90.3
92
N.A.
N.A.
80.2
81
46.8
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
100
N.A.
93.3
80
N.A.
66.6
66.6
N.A.
N.A.
80
73.3
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
N.A.
100
86.6
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
50.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
70
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
20
0
0
20
80
0
0
0
10
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
80
0
0
0
0
10
80
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
0
10
0
0
0
0
0
0
0
40
0
0
% K
% Leu:
0
10
10
70
10
0
0
0
0
0
20
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
10
20
0
0
% P
% Gln:
0
0
0
0
40
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
60
0
20
0
0
% R
% Ser:
0
0
0
10
0
0
0
10
10
0
0
80
10
0
0
% S
% Thr:
10
0
10
0
0
10
0
50
0
0
0
10
0
0
0
% T
% Val:
0
80
60
0
0
0
10
0
0
80
0
0
0
50
90
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _