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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD2
All Species:
23.94
Human Site:
T370
Identified Species:
58.52
UniProt:
Q8N2H3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2H3
NP_116098.2
581
63068
T370
E
R
I
S
Q
L
D
T
R
S
P
V
T
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105930
581
62770
T370
E
K
I
S
Q
L
D
T
R
S
P
V
T
K
I
Dog
Lupus familis
XP_534984
937
101613
T669
E
R
I
S
R
L
D
T
K
S
P
V
T
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3U4I7
580
62666
T369
K
R
I
S
Q
L
D
T
Q
S
P
V
T
K
I
Rat
Rattus norvegicus
Q68FT3
581
62861
T370
K
R
I
S
Q
L
D
T
Q
S
P
V
T
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423118
593
64444
T378
R
R
I
Q
Q
L
D
T
R
S
P
V
T
K
I
Frog
Xenopus laevis
NP_001088589
574
62793
A365
T
M
I
S
Q
F
N
A
K
S
P
V
T
K
I
Zebra Danio
Brachydanio rerio
XP_002664259
352
37788
G164
D
F
L
A
A
P
N
G
A
D
G
K
A
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500428
544
60408
N345
T
S
P
V
T
K
I
N
V
A
V
K
E
L
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310805
563
60894
Y353
R
A
L
K
Y
S
D
Y
S
S
A
T
T
K
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
52.4
N.A.
84.1
86
N.A.
N.A.
70.4
69.1
37.8
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
100
N.A.
98.1
56.8
N.A.
90.3
92
N.A.
N.A.
80.2
81
46.8
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
60
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
73.3
26.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
50.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
0
0
10
10
10
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
70
0
0
10
0
0
0
0
0
% D
% Glu:
30
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
0
0
10
0
0
0
0
0
0
0
80
% I
% Lys:
20
10
0
10
0
10
0
0
20
0
0
20
0
80
0
% K
% Leu:
0
0
20
0
0
60
0
0
0
0
0
0
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
70
0
0
0
20
% P
% Gln:
0
0
0
10
60
0
0
0
20
0
0
0
0
0
0
% Q
% Arg:
20
50
0
0
10
0
0
0
30
0
0
0
0
0
0
% R
% Ser:
0
10
0
60
0
10
0
0
10
80
0
0
0
0
0
% S
% Thr:
20
0
0
0
10
0
0
60
0
0
0
10
80
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
10
70
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _