KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD2
All Species:
11.82
Human Site:
Y162
Identified Species:
28.89
UniProt:
Q8N2H3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2H3
NP_116098.2
581
63068
Y162
D
A
Q
V
F
P
K
Y
E
E
F
M
H
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105930
581
62770
Y162
D
A
Q
V
F
P
R
Y
E
E
F
M
H
R
L
Dog
Lupus familis
XP_534984
937
101613
Y407
D
A
Q
A
F
P
K
Y
E
A
F
M
K
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U4I7
580
62666
E162
D
A
Q
A
F
P
R
E
E
F
M
K
R
L
V
Rat
Rattus norvegicus
Q68FT3
581
62861
Y162
D
A
Q
A
F
P
R
Y
E
E
F
M
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423118
593
64444
F176
A
Y
P
K
Y
E
V
F
M
G
R
L
V
S
A
Frog
Xenopus laevis
NP_001088589
574
62793
P170
R
L
V
L
A
I
D
P
L
L
D
A
P
P
L
Zebra Danio
Brachydanio rerio
XP_002664259
352
37788
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500428
544
60408
L158
M
D
Y
E
P
L
D
L
Q
K
P
I
H
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002310805
563
60894
S158
L
M
D
P
L
L
D
S
P
P
P
E
T
A
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
52.4
N.A.
84.1
86
N.A.
N.A.
70.4
69.1
37.8
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
100
N.A.
98.1
56.8
N.A.
90.3
92
N.A.
N.A.
80.2
81
46.8
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
40
80
N.A.
N.A.
0
6.6
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
73.3
N.A.
53.3
86.6
N.A.
N.A.
20
13.3
0
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
50.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
50
0
30
10
0
0
0
0
10
0
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
10
10
0
0
0
30
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
10
50
30
0
10
0
0
0
% E
% Phe:
0
0
0
0
50
0
0
10
0
10
40
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
20
0
0
10
0
10
20
10
0
% K
% Leu:
10
10
0
10
10
20
0
10
10
10
0
10
0
10
50
% L
% Met:
10
10
0
0
0
0
0
0
10
0
10
40
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
10
50
0
10
10
10
20
0
10
10
0
% P
% Gln:
0
0
50
0
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
0
0
30
0
0
0
10
0
10
30
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
10
20
0
0
10
0
0
0
0
0
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
10
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _