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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABHD12
All Species:
14.85
Human Site:
S20
Identified Species:
25.13
UniProt:
Q8N2K0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2K0
NP_001035937.1
398
45097
S20
E
R
C
A
A
A
G
S
S
S
S
G
S
A
A
Chimpanzee
Pan troglodytes
XP_522850
362
40684
R20
E
P
P
G
P
P
A
R
S
C
V
A
A
W
W
Rhesus Macaque
Macaca mulatta
XP_001102076
362
40830
C22
P
G
P
P
A
H
G
C
V
A
A
W
W
D
M
Dog
Lupus familis
XP_534202
545
60111
S167
E
R
C
A
A
S
G
S
S
S
S
G
S
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99LR1
398
45251
S20
E
R
C
A
A
S
G
S
S
S
S
G
S
A
A
Rat
Rattus norvegicus
Q6AYT7
398
45277
S20
E
R
C
A
A
S
G
S
S
S
S
G
S
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515209
427
47963
E21
N
Q
A
R
G
A
T
E
A
A
I
T
Q
G
L
Chicken
Gallus gallus
Q5ZIN0
381
43837
A20
E
R
A
A
A
A
P
A
P
L
D
K
G
C
S
Frog
Xenopus laevis
Q6IRP4
336
38243
S9
E
K
H
W
V
L
W
S
C
A
E
R
W
L
L
Zebra Danio
Brachydanio rerio
Q08C93
382
43267
D20
S
F
T
A
T
L
T
D
G
S
S
D
L
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611397
393
45557
F24
L
Q
A
C
L
L
I
F
F
L
I
F
V
V
L
Honey Bee
Apis mellifera
XP_395396
359
41457
W20
P
F
A
A
L
D
I
W
Y
T
K
I
Y
L
F
Nematode Worm
Caenorhab. elegans
NP_505054
345
39613
I18
P
L
L
L
C
I
T
I
L
V
L
S
I
V
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42840
284
32290
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
41.2
68.9
N.A.
93.2
93.4
N.A.
41.6
82.4
24.3
66.5
N.A.
31.6
33.6
34.1
N.A.
Protein Similarity:
100
56.2
56.5
71
N.A.
96.2
96.4
N.A.
57.8
89.1
39.4
78.1
N.A.
51
52.5
49.7
N.A.
P-Site Identity:
100
13.3
13.3
93.3
N.A.
93.3
93.3
N.A.
6.6
33.3
13.3
20
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
20
26.6
100
N.A.
100
100
N.A.
26.6
46.6
26.6
20
N.A.
6.6
13.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
50
43
22
8
8
8
22
8
8
8
29
29
% A
% Cys:
0
0
29
8
8
0
0
8
8
8
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
0
8
8
0
8
0
% D
% Glu:
50
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
15
0
0
0
0
0
8
8
0
0
8
0
0
8
% F
% Gly:
0
8
0
8
8
0
36
0
8
0
0
29
8
8
0
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
15
8
0
0
15
8
8
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
8
8
0
8
0
% K
% Leu:
8
8
8
8
15
22
0
0
8
15
8
0
8
15
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
22
8
15
8
8
8
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
36
0
8
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
8
0
0
0
0
22
0
36
36
36
36
8
29
0
8
% S
% Thr:
0
0
8
0
8
0
22
0
0
8
0
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
8
8
8
0
8
15
0
% V
% Trp:
0
0
0
8
0
0
8
8
0
0
0
8
15
8
8
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _