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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABHD12
All Species:
19.7
Human Site:
Y345
Identified Species:
33.33
UniProt:
Q8N2K0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2K0
NP_001035937.1
398
45097
Y345
F
Q
L
G
R
K
L
Y
S
I
A
A
P
A
R
Chimpanzee
Pan troglodytes
XP_522850
362
40684
E310
D
D
R
T
V
P
L
E
Y
G
K
K
L
Y
E
Rhesus Macaque
Macaca mulatta
XP_001102076
362
40830
E310
D
D
R
T
V
P
L
E
Y
G
K
K
L
Y
E
Dog
Lupus familis
XP_534202
545
60111
Y492
F
Q
L
G
R
K
L
Y
N
I
A
A
P
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99LR1
398
45251
Y345
F
H
L
G
R
K
L
Y
N
I
A
A
P
S
R
Rat
Rattus norvegicus
Q6AYT7
398
45277
Y345
F
H
L
G
R
K
L
Y
N
I
A
A
P
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515209
427
47963
E375
D
D
K
T
V
P
L
E
Q
G
K
R
L
Y
D
Chicken
Gallus gallus
Q5ZIN0
381
43837
Y328
F
H
L
G
K
K
L
Y
N
I
A
A
T
S
R
Frog
Xenopus laevis
Q6IRP4
336
38243
P284
K
Q
L
Y
E
L
S
P
S
R
T
K
R
L
A
Zebra Danio
Brachydanio rerio
Q08C93
382
43267
K328
V
V
P
F
Q
L
G
K
K
L
Y
D
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611397
393
45557
Y341
F
N
L
G
Y
R
L
Y
R
I
A
L
D
G
R
Honey Bee
Apis mellifera
XP_395396
359
41457
F306
F
A
L
G
E
K
L
F
K
A
A
I
N
Y
H
Nematode Worm
Caenorhab. elegans
NP_505054
345
39613
E293
K
L
G
R
A
L
Y
E
A
A
K
D
A
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42840
284
32290
E232
F
L
S
G
L
K
D
E
I
V
P
P
F
H
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
41.2
68.9
N.A.
93.2
93.4
N.A.
41.6
82.4
24.3
66.5
N.A.
31.6
33.6
34.1
N.A.
Protein Similarity:
100
56.2
56.5
71
N.A.
96.2
96.4
N.A.
57.8
89.1
39.4
78.1
N.A.
51
52.5
49.7
N.A.
P-Site Identity:
100
6.6
6.6
86.6
N.A.
80
80
N.A.
6.6
66.6
20
6.6
N.A.
53.3
40
6.6
N.A.
P-Site Similarity:
100
6.6
6.6
100
N.A.
93.3
93.3
N.A.
6.6
86.6
20
20
N.A.
60
46.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
8
15
50
36
8
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
22
0
0
0
0
8
0
0
0
0
15
8
0
8
% D
% Glu:
0
0
0
0
15
0
0
36
0
0
0
0
0
8
15
% E
% Phe:
58
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
0
8
58
0
0
8
0
0
22
0
0
0
8
0
% G
% His:
0
22
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
43
0
8
0
0
0
% I
% Lys:
15
0
8
0
8
50
0
8
15
0
29
22
0
0
0
% K
% Leu:
0
15
58
0
8
22
72
0
0
8
0
8
29
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
29
0
0
0
8
0
0
% N
% Pro:
0
0
8
0
0
22
0
8
0
0
8
8
29
0
0
% P
% Gln:
0
22
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
15
8
29
8
0
0
8
8
0
8
8
0
50
% R
% Ser:
0
0
8
0
0
0
8
0
15
0
0
0
0
29
0
% S
% Thr:
0
0
0
22
0
0
0
0
0
0
8
0
8
0
0
% T
% Val:
8
8
0
0
22
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
43
15
0
8
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _