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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM86A
All Species:
25.45
Human Site:
S36
Identified Species:
62.22
UniProt:
Q8N2M4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2M4
NP_699178.1
240
26398
S36
W
L
P
S
S
S
P
S
W
V
S
T
L
I
K
Chimpanzee
Pan troglodytes
XP_521860
403
43950
S199
W
L
P
S
S
S
P
S
W
V
S
T
L
I
K
Rhesus Macaque
Macaca mulatta
XP_001096748
240
26380
S36
W
L
P
S
S
S
P
S
W
V
S
T
L
I
K
Dog
Lupus familis
XP_542526
316
34107
S112
W
L
P
S
T
S
P
S
W
V
S
A
L
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8N3
241
26255
S36
W
L
P
S
S
S
P
S
W
V
S
A
L
I
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507840
223
23804
C40
W
L
P
A
D
R
P
C
L
A
S
A
L
V
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090481
237
26538
S36
W
L
P
T
S
S
P
S
W
F
S
A
L
I
K
Zebra Danio
Brachydanio rerio
NP_001013530
237
26037
S36
W
L
P
T
S
S
P
S
W
F
S
A
L
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393044
231
25598
L36
L
A
E
Q
P
S
L
L
T
A
C
F
K
C
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789121
227
24786
V38
L
L
K
C
L
P
I
V
C
L
C
G
L
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
98.3
69.9
N.A.
88.3
N.A.
N.A.
42.5
N.A.
72.5
70.8
N.A.
N.A.
41.2
N.A.
40.4
Protein Similarity:
100
59.3
98.7
72.1
N.A.
92.5
N.A.
N.A.
55.8
N.A.
83.3
84.1
N.A.
N.A.
58.7
N.A.
58.3
P-Site Identity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
46.6
N.A.
80
80
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
60
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
20
0
50
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
10
10
0
20
0
0
10
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
20
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
70
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
80
% K
% Leu:
20
90
0
0
10
0
10
10
10
10
0
0
90
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
80
0
10
10
80
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
50
60
80
0
70
0
0
80
0
0
0
0
% S
% Thr:
0
0
0
20
10
0
0
0
10
0
0
30
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
50
0
0
0
20
0
% V
% Trp:
80
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _