KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSR2
All Species:
27.88
Human Site:
Y220
Identified Species:
55.76
UniProt:
Q8N2R0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2R0
NP_001135934.1
312
35513
Y220
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Chimpanzee
Pan troglodytes
XP_001150334
329
36355
L217
R
K
P
S
R
G
R
L
P
S
K
T
K
K
E
Rhesus Macaque
Macaca mulatta
XP_001095141
312
35508
Y220
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Dog
Lupus familis
XP_539101
312
35536
Y220
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZD1
312
35435
Y220
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Rat
Rattus norvegicus
Q6AY34
276
30495
H190
K
S
Y
N
L
L
I
H
E
R
T
H
T
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001163815
412
43852
Y220
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Frog
Xenopus laevis
Q0IHB8
271
30295
Y185
G
R
H
F
T
K
S
Y
N
L
L
I
H
E
R
Zebra Danio
Brachydanio rerio
Q5XJQ7
264
29545
F178
K
K
E
F
V
C
K
F
C
G
R
H
F
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQS7
578
58436
Y443
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41995
242
27529
F156
T
H
T
N
E
R
P
F
H
C
E
T
C
G
K
Sea Urchin
Strong. purpuratus
XP_781182
380
41525
Y250
D
H
L
R
D
H
R
Y
I
H
S
K
E
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
99.6
98.7
N.A.
98
83
N.A.
N.A.
61.8
78.5
57.3
N.A.
32.8
N.A.
30.1
43.4
Protein Similarity:
100
79.6
100
99.3
N.A.
99
83.3
N.A.
N.A.
66
83.6
65.7
N.A.
38.9
N.A.
44.8
52.6
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
N.A.
100
6.6
0
N.A.
100
N.A.
6.6
100
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
N.A.
100
13.3
13.3
N.A.
100
N.A.
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
9
0
0
9
0
0
% C
% Asp:
59
0
0
0
59
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
9
0
9
0
0
0
9
0
9
0
59
9
17
% E
% Phe:
0
0
0
17
0
0
0
17
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
0
9
0
0
0
9
0
0
0
9
0
% G
% His:
0
67
9
0
0
59
0
9
9
59
0
17
9
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
59
0
0
9
0
0
0
% I
% Lys:
17
17
0
0
0
9
9
0
0
0
9
59
9
67
17
% K
% Leu:
0
0
59
0
9
9
0
9
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
59
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
9
0
59
9
9
67
0
0
9
9
0
0
0
9
% R
% Ser:
0
9
0
9
0
0
9
0
0
9
59
0
0
0
0
% S
% Thr:
9
0
9
0
9
0
0
0
0
0
9
17
9
9
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _