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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS4
All Species:
24.24
Human Site:
T280
Identified Species:
59.26
UniProt:
Q8N2W9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2W9
NP_056981.2
510
56504
T280
L
Y
L
V
R
Q
L
T
S
S
E
L
L
Q
R
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S404
V
Y
L
V
K
Q
L
S
S
T
V
L
L
Q
R
Rhesus Macaque
Macaca mulatta
XP_001101401
371
42000
V176
S
R
E
L
Q
P
G
V
K
A
V
Q
V
V
L
Dog
Lupus familis
XP_542167
430
48293
N234
K
R
P
C
R
P
I
N
L
T
H
L
M
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM05
507
55551
T273
L
Y
L
V
R
Q
L
T
S
S
D
L
L
Q
R
Rat
Rattus norvegicus
O70260
628
68345
T281
V
Y
L
V
R
Q
L
T
A
G
T
L
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
S388
V
Y
L
V
K
Q
L
S
S
T
V
L
L
Q
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087978
501
55855
T287
L
Y
L
V
R
Q
R
T
S
S
E
L
L
Q
R
Zebra Danio
Brachydanio rerio
NP_998568
505
55791
T265
V
Y
L
V
R
V
F
T
S
G
E
L
F
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
N381
V
Y
F
V
H
R
V
N
S
D
I
L
F
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
72.5
80.3
N.A.
90.1
41.2
N.A.
34.6
N.A.
79
59.6
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
100
46.2
72.5
81.7
N.A.
93.5
55.2
N.A.
47.4
N.A.
87.2
72.1
N.A.
N.A.
N.A.
36.3
N.A.
P-Site Identity:
100
66.6
0
13.3
N.A.
93.3
66.6
N.A.
66.6
N.A.
93.3
53.3
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
93.3
26.6
33.3
N.A.
100
86.6
N.A.
93.3
N.A.
93.3
66.6
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
30
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
20
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
20
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
20
0
0
0
10
0
0
0
0
10
10
% K
% Leu:
30
0
70
10
0
0
50
0
10
0
0
90
60
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
20
0
0
0
0
0
10
0
% N
% Pro:
0
0
10
0
0
20
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
60
0
0
0
0
0
10
0
60
10
% Q
% Arg:
0
20
0
0
60
10
10
0
0
0
0
0
0
0
60
% R
% Ser:
10
0
0
0
0
0
0
20
70
30
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
30
10
0
0
0
0
% T
% Val:
50
0
0
80
0
10
10
10
0
0
30
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
80
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _