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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGGF1 All Species: 16.36
Human Site: S543 Identified Species: 32.73
UniProt: Q8N302 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N302 NP_060516.2 714 80977 S543 R L D K K D E S F V G P T L S
Chimpanzee Pan troglodytes XP_526886 714 80982 S543 R L D K K D E S F V G P T L S
Rhesus Macaque Macaca mulatta XP_001106588 710 80468 S539 R L D K K D E S F V G P T L S
Dog Lupus familis XP_536317 711 80206 C540 R L D K K D E C F V G P A L S
Cat Felis silvestris
Mouse Mus musculus Q7TN31 711 79427 P540 R L D R K D E P L V G P A L S
Rat Rattus norvegicus XP_001060407 705 79061 P534 R L D K K D E P L V G P A L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513838 745 83514 S574 R L D K K D E S S V S P A L S
Chicken Gallus gallus XP_414679 690 77765 S519 R L D K K K E S S V C P A L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073451 774 87501 E600 L S R H K K D E S S G A V L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611023 601 66926 S455 S S T A S V L S H K E Q L K K
Honey Bee Apis mellifera XP_394532 554 62863 E408 Q Q N N N A E E N K S S K K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783785 1289 142207 W845 K M L K K M G W Q E G Q S L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.9 88.8 N.A. 78 78 N.A. 65.3 60.5 N.A. 43.7 N.A. 27.1 27.5 N.A. 23.5
Protein Similarity: 100 99.4 97.7 92.3 N.A. 88 86.5 N.A. 75.9 73.1 N.A. 60.3 N.A. 43.8 46 N.A. 37.5
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. 80 73.3 N.A. 26.6 N.A. 6.6 6.6 N.A. 26.6
P-Site Similarity: 100 100 100 86.6 N.A. 80 80 N.A. 80 73.3 N.A. 33.3 N.A. 6.6 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 0 0 9 42 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % C
% Asp: 0 0 67 0 0 59 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 75 17 0 9 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 67 0 0 0 9 % G
% His: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 67 84 17 0 0 0 17 0 0 9 17 9 % K
% Leu: 9 67 9 0 0 0 9 0 17 0 0 0 9 84 0 % L
% Met: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 9 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 17 0 0 0 67 0 0 0 % P
% Gln: 9 9 0 0 0 0 0 0 9 0 0 17 0 0 9 % Q
% Arg: 67 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 17 0 0 9 0 0 50 25 9 17 9 9 0 75 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 0 0 25 0 0 % T
% Val: 0 0 0 0 0 9 0 0 0 67 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _