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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGGF1 All Species: 27.58
Human Site: T445 Identified Species: 55.15
UniProt: Q8N302 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N302 NP_060516.2 714 80977 T445 R E K D M E H T L R I P E V G
Chimpanzee Pan troglodytes XP_526886 714 80982 T445 R E K D M E H T L R I P E V G
Rhesus Macaque Macaca mulatta XP_001106588 710 80468 T441 R E K D M E H T L R I P E V G
Dog Lupus familis XP_536317 711 80206 T442 R E K D M E H T L R I P E V G
Cat Felis silvestris
Mouse Mus musculus Q7TN31 711 79427 T442 R E K D M E H T V R I P E V A
Rat Rattus norvegicus XP_001060407 705 79061 T436 R E K D M E H T V R I P E V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513838 745 83514 T476 R E K D M A H T L R I P E V G
Chicken Gallus gallus XP_414679 690 77765 E426 G H T L Q I P E V G V S K F H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073451 774 87501 A503 R E K D M N H A I R I P E M G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611023 601 66926 S363 I I P D V N V S K C H L K F K
Honey Bee Apis mellifera XP_394532 554 62863 V316 R E G D H S V V I P D I N I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783785 1289 142207 I658 G R E G S N H I L L V P E L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.9 88.8 N.A. 78 78 N.A. 65.3 60.5 N.A. 43.7 N.A. 27.1 27.5 N.A. 23.5
Protein Similarity: 100 99.4 97.7 92.3 N.A. 88 86.5 N.A. 75.9 73.1 N.A. 60.3 N.A. 43.8 46 N.A. 37.5
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 93.3 0 N.A. 73.3 N.A. 6.6 20 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 20 N.A. 86.6 N.A. 26.6 33.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 84 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 75 9 0 0 50 0 9 0 0 0 0 75 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % F
% Gly: 17 0 9 9 0 0 0 0 0 9 0 0 0 0 59 % G
% His: 0 9 0 0 9 0 75 0 0 0 9 0 0 0 9 % H
% Ile: 9 9 0 0 0 9 0 9 17 0 67 9 0 9 0 % I
% Lys: 0 0 67 0 0 0 0 0 9 0 0 0 17 0 9 % K
% Leu: 0 0 0 9 0 0 0 0 50 9 0 9 0 9 0 % L
% Met: 0 0 0 0 67 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 25 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 9 0 0 0 9 0 0 9 0 75 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 75 9 0 0 0 0 0 0 0 67 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 9 0 9 0 0 0 9 0 0 9 % S
% Thr: 0 0 9 0 0 0 0 59 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 17 9 25 0 17 0 0 59 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _