KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGGF1
All Species:
28.18
Human Site:
Y224
Identified Species:
56.36
UniProt:
Q8N302
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N302
NP_060516.2
714
80977
Y224
F
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Chimpanzee
Pan troglodytes
XP_526886
714
80982
Y224
F
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Rhesus Macaque
Macaca mulatta
XP_001106588
710
80468
Y220
F
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Dog
Lupus familis
XP_536317
711
80206
Y221
F
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN31
711
79427
Y225
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Y
Rat
Rattus norvegicus
XP_001060407
705
79061
D219
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513838
745
83514
Y247
Y
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Chicken
Gallus gallus
XP_414679
690
77765
Y218
C
D
V
E
S
G
R
Y
Q
F
H
S
R
V
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073451
774
87501
Y235
Y
D
H
S
T
G
F
Y
Y
D
S
S
S
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611023
601
66926
L155
Y
Y
N
A
E
Y
G
L
Y
Y
D
G
N
N
G
Honey Bee
Apis mellifera
XP_394532
554
62863
Q108
T
S
T
D
I
I
Q
Q
V
K
E
A
A
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783785
1289
142207
Y368
Y
D
Y
N
S
G
Y
Y
Y
D
P
N
N
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96.9
88.8
N.A.
78
78
N.A.
65.3
60.5
N.A.
43.7
N.A.
27.1
27.5
N.A.
23.5
Protein Similarity:
100
99.4
97.7
92.3
N.A.
88
86.5
N.A.
75.9
73.1
N.A.
60.3
N.A.
43.8
46
N.A.
37.5
P-Site Identity:
100
100
100
100
N.A.
6.6
0
N.A.
93.3
20
N.A.
80
N.A.
13.3
0
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
20
26.6
N.A.
100
26.6
N.A.
93.3
N.A.
33.3
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
67
0
9
0
0
0
9
9
59
9
0
0
0
9
% D
% Glu:
0
0
0
9
9
0
0
0
0
9
17
42
0
9
0
% E
% Phe:
34
0
0
0
9
9
50
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
67
9
0
0
0
0
9
0
0
9
% G
% His:
9
9
50
0
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
9
9
59
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
0
0
9
17
59
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
9
9
0
0
9
9
50
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% R
% Ser:
0
17
9
50
17
0
0
0
9
9
50
17
9
0
9
% S
% Thr:
9
0
17
9
50
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
9
9
0
0
17
25
75
67
9
0
0
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _