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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGGF1
All Species:
27.27
Human Site:
Y497
Identified Species:
54.55
UniProt:
Q8N302
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N302
NP_060516.2
714
80977
Y497
P
K
T
K
C
D
P
Y
V
L
E
H
G
D
E
Chimpanzee
Pan troglodytes
XP_526886
714
80982
Y497
P
K
T
K
C
D
P
Y
V
L
E
H
G
D
E
Rhesus Macaque
Macaca mulatta
XP_001106588
710
80468
Y493
P
K
T
K
C
D
P
Y
V
L
E
H
G
D
E
Dog
Lupus familis
XP_536317
711
80206
Y494
P
K
T
K
C
D
P
Y
V
L
E
H
G
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN31
711
79427
Y494
P
K
T
K
C
D
P
Y
V
L
E
H
G
D
E
Rat
Rattus norvegicus
XP_001060407
705
79061
Y488
P
K
T
K
C
D
P
Y
I
L
E
H
G
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513838
745
83514
Y528
P
K
T
K
C
D
P
Y
I
L
E
H
G
D
E
Chicken
Gallus gallus
XP_414679
690
77765
G478
D
P
Y
I
L
E
H
G
D
E
V
K
I
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073451
774
87501
C555
P
K
V
R
C
D
P
C
P
L
T
H
G
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611023
601
66926
R415
V
I
T
L
G
Q
T
R
L
L
C
H
V
H
E
Honey Bee
Apis mellifera
XP_394532
554
62863
V368
Q
E
S
D
P
H
E
V
S
H
G
S
I
V
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783785
1289
142207
P710
K
S
R
V
K
S
D
P
Q
P
L
S
H
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96.9
88.8
N.A.
78
78
N.A.
65.3
60.5
N.A.
43.7
N.A.
27.1
27.5
N.A.
23.5
Protein Similarity:
100
99.4
97.7
92.3
N.A.
88
86.5
N.A.
75.9
73.1
N.A.
60.3
N.A.
43.8
46
N.A.
37.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
6.6
N.A.
66.6
N.A.
26.6
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
N.A.
73.3
N.A.
33.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
67
0
0
9
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
9
0
67
9
0
9
0
0
0
0
67
9
% D
% Glu:
0
9
0
0
0
9
9
0
0
9
59
0
0
0
84
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
9
0
67
9
0
% G
% His:
0
0
0
0
0
9
9
0
0
9
0
75
9
9
0
% H
% Ile:
0
9
0
9
0
0
0
0
17
0
0
0
17
0
0
% I
% Lys:
9
67
0
59
9
0
0
0
0
0
0
9
0
9
0
% K
% Leu:
0
0
0
9
9
0
0
0
9
75
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
9
0
0
9
0
67
9
9
9
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
9
% Q
% Arg:
0
0
9
9
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
0
9
0
0
9
0
0
17
0
0
0
% S
% Thr:
0
0
67
0
0
0
9
0
0
0
9
0
0
0
0
% T
% Val:
9
0
9
9
0
0
0
9
42
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _