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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIER2
All Species:
9.39
Human Site:
S490
Identified Species:
22.96
UniProt:
Q8N344
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N344
NP_060020.1
545
59944
S490
I
S
S
H
V
D
L
S
G
D
P
E
E
T
V
Chimpanzee
Pan troglodytes
XP_001142293
550
61391
S472
L
N
P
M
N
M
C
S
E
E
S
E
R
P
A
Rhesus Macaque
Macaca mulatta
XP_001090898
545
59474
S490
I
S
S
R
V
D
L
S
G
D
P
E
G
T
V
Dog
Lupus familis
XP_855258
1002
107822
N947
I
S
S
H
A
D
M
N
G
E
P
E
E
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U3N0
541
59249
S486
V
S
S
P
V
A
L
S
E
D
T
A
E
P
M
Rat
Rattus norvegicus
NP_001102207
398
44926
R348
Y
L
W
K
K
S
E
R
Y
D
Y
F
A
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507861
561
61996
G483
L
N
P
A
D
V
C
G
E
E
S
E
R
P
A
Chicken
Gallus gallus
Q5ZKT9
513
58071
S461
L
D
P
K
V
A
H
S
T
S
R
S
E
N
D
Frog
Xenopus laevis
Q7T105
495
56289
D445
N
R
E
N
V
T
D
D
S
R
F
S
H
T
S
Zebra Danio
Brachydanio rerio
XP_693146
488
54708
P438
I
S
R
R
H
S
V
P
S
S
H
L
T
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.6
95.5
45.5
N.A.
81.2
63.4
N.A.
37
34.8
36.8
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.3
96.5
48.5
N.A.
86.7
68.2
N.A.
52.7
49.3
53.5
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
86.6
66.6
N.A.
46.6
6.6
N.A.
6.6
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
86.6
86.6
N.A.
60
6.6
N.A.
26.6
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
20
0
0
0
0
0
10
10
10
20
% A
% Cys:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
30
10
10
0
40
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
10
0
30
30
0
50
40
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
30
0
0
0
10
0
10
% G
% His:
0
0
0
20
10
0
10
0
0
0
10
0
10
0
0
% H
% Ile:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
20
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
30
10
0
0
0
0
30
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
10
% M
% Asn:
10
20
0
10
10
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
30
10
0
0
0
10
0
0
30
0
0
30
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% Q
% Arg:
0
10
10
20
0
0
0
10
0
10
10
0
20
0
0
% R
% Ser:
0
50
40
0
0
20
0
50
20
20
20
20
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
10
0
10
0
10
30
0
% T
% Val:
10
0
0
0
50
10
10
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _