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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOS All Species: 7.27
Human Site: S324 Identified Species: 26.67
UniProt: Q8N350 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N350 NP_689982.2 725 75822 S324 H A S L D G A S P Y F K V K K
Chimpanzee Pan troglodytes XP_001172389 471 50313 N129 T G R R V S F N E A A L F E Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_855168 711 74195 F329 G S P K R H H F Q R Q R A A S
Cat Felis silvestris
Mouse Mus musculus Q66L44 709 75403 S306 H A S L D G A S P Y F K V K K
Rat Rattus norvegicus NP_001101540 431 45711 S89 Y I A S A G D S V A F P P P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516494 423 45127 V81 H L P P L K I V T I H E C D P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685582 541 59368 S199 T R P V A K S S L S I F Q P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.9 N.A. 55.5 N.A. 75.1 48.4 N.A. 26.7 N.A. N.A. 32.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57 N.A. 61.6 N.A. 79.3 50.9 N.A. 34 N.A. N.A. 45 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 0 N.A. 100 20 N.A. 6.6 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. 13.3 N.A. 100 40 N.A. 13.3 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 15 0 29 0 29 0 0 29 15 0 15 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % C
% Asp: 0 0 0 0 29 0 15 0 0 0 0 0 0 15 0 % D
% Glu: 0 0 0 0 0 0 0 0 15 0 0 15 0 15 0 % E
% Phe: 0 0 0 0 0 0 15 15 0 0 43 15 15 0 0 % F
% Gly: 15 15 0 0 0 43 0 0 0 0 0 0 0 0 0 % G
% His: 43 0 0 0 0 15 15 0 0 0 15 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 15 0 0 15 15 0 0 0 0 % I
% Lys: 0 0 0 15 0 29 0 0 0 0 0 29 0 29 29 % K
% Leu: 0 15 0 29 15 0 0 0 15 0 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 0 0 43 15 0 0 0 0 29 0 0 15 15 29 29 % P
% Gln: 0 0 0 0 0 0 0 0 15 0 15 0 15 0 15 % Q
% Arg: 0 15 15 15 15 0 0 0 0 15 0 15 0 0 15 % R
% Ser: 0 15 29 15 0 15 15 58 0 15 0 0 0 0 15 % S
% Thr: 29 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % T
% Val: 0 0 0 15 15 0 0 15 15 0 0 0 29 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _