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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2orf18
All Species:
13.33
Human Site:
S354
Identified Species:
26.67
UniProt:
Q8N357
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N357
NP_060347.2
371
40214
S354
G
R
P
L
A
E
E
S
E
Q
E
R
L
L
G
Chimpanzee
Pan troglodytes
XP_515345
371
40224
S354
G
R
P
L
A
E
E
S
E
Q
E
R
L
L
G
Rhesus Macaque
Macaca mulatta
XP_001087194
371
40312
S354
G
R
P
L
A
E
E
S
E
Q
E
R
L
L
G
Dog
Lupus familis
XP_540118
371
40361
G354
G
R
P
P
A
E
E
G
E
H
E
R
L
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE96
372
40960
E354
R
W
R
L
P
T
Q
E
G
E
Q
E
R
L
L
Rat
Rattus norvegicus
Q5RKH7
372
41074
E354
R
W
R
H
P
T
Q
E
G
E
Q
E
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520514
368
40152
S351
G
Q
L
S
S
E
E
S
E
R
E
S
L
L
S
Chicken
Gallus gallus
XP_428633
371
40427
A354
S
R
A
D
G
S
E
A
E
R
E
G
L
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002559
374
41128
E355
F
A
R
E
Q
I
T
E
E
G
N
V
P
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650136
381
42788
Y358
R
A
A
V
A
R
W
Y
R
A
R
Y
V
D
L
Honey Bee
Apis mellifera
XP_395781
379
42421
P359
Y
H
L
G
R
H
R
P
P
A
H
D
R
E
R
Nematode Worm
Caenorhab. elegans
NP_495226
393
43880
A363
L
P
N
L
S
S
H
A
N
C
A
R
C
W
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
93.5
N.A.
86.8
88.1
N.A.
85.4
80.3
N.A.
73.2
N.A.
34.6
47.2
48.5
N.A.
Protein Similarity:
100
100
99.1
97
N.A.
93
93.2
N.A.
91.3
88.1
N.A.
83.6
N.A.
51.7
63.3
64.8
N.A.
P-Site Identity:
100
100
100
80
N.A.
13.3
6.6
N.A.
53.3
40
N.A.
6.6
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
33.3
26.6
N.A.
73.3
53.3
N.A.
6.6
N.A.
20
0
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
17
0
42
0
0
17
0
17
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
9
0
% D
% Glu:
0
0
0
9
0
42
50
25
59
17
50
17
0
17
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
0
9
9
0
0
9
17
9
0
9
0
0
34
% G
% His:
0
9
0
9
0
9
9
0
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
17
42
0
0
0
0
0
0
0
0
50
67
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
9
0
0
0
9
% N
% Pro:
0
9
34
9
17
0
0
9
9
0
0
0
9
0
0
% P
% Gln:
0
9
0
0
9
0
17
0
0
25
17
0
0
0
0
% Q
% Arg:
25
42
25
0
9
9
9
0
9
17
9
42
25
0
17
% R
% Ser:
9
0
0
9
17
17
0
34
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% V
% Trp:
0
17
0
0
0
0
9
0
0
0
0
0
0
9
0
% W
% Tyr:
9
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _