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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARP8 All Species: 27.88
Human Site: S410 Identified Species: 68.15
UniProt: Q8N3A8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3A8 NP_078891.2 854 95871 S410 P H K L L S R S Y S S N L R M
Chimpanzee Pan troglodytes XP_001151176 833 93349 S411 N H K L L S K S Y S S A P K S
Rhesus Macaque Macaca mulatta XP_001093952 854 95810 S410 P H K L L S R S Y S S N L R M
Dog Lupus familis XP_853766 852 95417 S408 P H K L L S R S Y S S N L R M
Cat Felis silvestris
Mouse Mus musculus Q3UD82 852 95541 S409 P H K L L S R S Y S S N L R M
Rat Rattus norvegicus XP_001068789 852 95545 S409 P H K L L S R S Y S S N L R M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514099 907 100542 S461 P H K L L S R S Y S S N L R V
Chicken Gallus gallus XP_424786 876 98087 Y430 H K L L S R S Y S S N L R M E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070643 859 96370 H409 D G G A L K P H R L L G R S C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783307 627 70977 S209 I S F S R S S S S M S Q S P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.8 97.3 N.A. 96.1 96.5 N.A. 82.3 85.7 N.A. 80.2 N.A. N.A. N.A. N.A. 38.2
Protein Similarity: 100 97 99.1 98.8 N.A. 97.7 97.7 N.A. 85.8 89.7 N.A. 88.5 N.A. N.A. N.A. N.A. 52.4
P-Site Identity: 100 60 100 100 N.A. 100 100 N.A. 93.3 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 73.3 100 100 N.A. 100 100 N.A. 100 20 N.A. 6.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 10 70 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 70 0 0 10 10 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 10 80 80 0 0 0 0 10 10 10 60 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 50 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 10 60 0 0 0 % N
% Pro: 60 0 0 0 0 0 10 0 0 0 0 0 10 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 10 10 60 0 10 0 0 0 20 60 0 % R
% Ser: 0 10 0 10 10 80 20 80 20 80 80 0 10 10 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 70 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _