KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP8
All Species:
13.33
Human Site:
S53
Identified Species:
32.59
UniProt:
Q8N3A8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3A8
NP_078891.2
854
95871
S53
G
P
R
S
V
S
Y
S
V
H
V
S
E
D
Y
Chimpanzee
Pan troglodytes
XP_001151176
833
93349
E52
V
S
S
S
E
N
D
E
D
V
L
V
T
T
E
Rhesus Macaque
Macaca mulatta
XP_001093952
854
95810
A53
G
S
R
S
V
S
Y
A
V
H
V
S
E
D
Y
Dog
Lupus familis
XP_853766
852
95417
V52
P
K
S
V
S
Y
S
V
H
V
S
E
D
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UD82
852
95541
S53
G
P
K
S
V
S
Y
S
V
H
V
S
E
D
Y
Rat
Rattus norvegicus
XP_001068789
852
95545
S53
G
P
K
S
V
S
Y
S
V
H
V
S
E
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514099
907
100542
P104
D
T
Q
T
P
P
L
P
S
P
T
S
E
A
P
Chicken
Gallus gallus
XP_424786
876
98087
E73
E
S
T
K
W
K
Q
E
R
V
W
D
C
T
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070643
859
96370
S53
G
P
K
R
V
S
Y
S
V
H
V
S
D
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783307
627
70977
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.8
97.3
N.A.
96.1
96.5
N.A.
82.3
85.7
N.A.
80.2
N.A.
N.A.
N.A.
N.A.
38.2
Protein Similarity:
100
97
99.1
98.8
N.A.
97.7
97.7
N.A.
85.8
89.7
N.A.
88.5
N.A.
N.A.
N.A.
N.A.
52.4
P-Site Identity:
100
6.6
86.6
0
N.A.
93.3
93.3
N.A.
13.3
0
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
93.3
6.6
N.A.
100
100
N.A.
26.6
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
10
0
0
10
20
50
0
% D
% Glu:
10
0
0
0
10
0
0
20
0
0
0
10
50
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
50
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
30
10
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
40
0
0
10
10
0
10
0
10
0
0
0
0
20
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
20
10
0
0
0
0
10
0
0
0
0
0
10
% R
% Ser:
0
30
20
50
10
50
10
40
10
0
10
60
0
0
0
% S
% Thr:
0
10
10
10
0
0
0
0
0
0
10
0
10
20
0
% T
% Val:
10
0
0
10
50
0
0
10
50
30
50
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
50
0
0
0
0
0
0
10
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _