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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARP8 All Species: 31.82
Human Site: Y602 Identified Species: 77.78
UniProt: Q8N3A8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3A8 NP_078891.2 854 95871 Y602 F N P R K K N Y D R V M K A L
Chimpanzee Pan troglodytes XP_001151176 833 93349 D589 D R V M K A L D S I T S I R E
Rhesus Macaque Macaca mulatta XP_001093952 854 95810 Y602 F N P R K K N Y D R V M K A L
Dog Lupus familis XP_853766 852 95417 Y600 F N P R K K N Y D R V M K A L
Cat Felis silvestris
Mouse Mus musculus Q3UD82 852 95541 Y600 F N P R K K N Y D R V M K A L
Rat Rattus norvegicus XP_001068789 852 95545 Y600 F N P R K K N Y D R V M K A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514099 907 100542 Y654 F N P R K K N Y D R V M K A L
Chicken Gallus gallus XP_424786 876 98087 Y623 F N P R K K N Y D R V M K A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070643 859 96370 Y607 F N P R K K D Y D R V M R A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783307 627 70977 L387 K K K N F D R L E S T L D K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.8 97.3 N.A. 96.1 96.5 N.A. 82.3 85.7 N.A. 80.2 N.A. N.A. N.A. N.A. 38.2
Protein Similarity: 100 97 99.1 98.8 N.A. 97.7 97.7 N.A. 85.8 89.7 N.A. 88.5 N.A. N.A. N.A. N.A. 52.4
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 0 0 80 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 10 10 80 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % E
% Phe: 80 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % I
% Lys: 10 10 10 0 90 80 0 0 0 0 0 0 70 10 0 % K
% Leu: 0 0 0 0 0 0 10 10 0 0 0 10 0 0 80 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 80 0 0 0 % M
% Asn: 0 80 0 10 0 0 70 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 80 0 0 10 0 0 80 0 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 10 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 80 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _