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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD3 All Species: 20.61
Human Site: S233 Identified Species: 34.87
UniProt: Q8N3E9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3E9 NP_588614.1 789 89258 S233 L F K E C D H S N N D R L E G
Chimpanzee Pan troglodytes XP_001142960 788 88666 S233 L F K E C D H S N N D R L E G
Rhesus Macaque Macaca mulatta XP_001115230 785 88822 S229 L F K E C D H S N N D R L E G
Dog Lupus familis XP_548052 697 79208 R202 H R Y S G E D R V L S A P E L
Cat Felis silvestris
Mouse Mus musculus Q8K2J0 785 88588 S229 L F K E C D H S N N E R L E G
Rat Rattus norvegicus P10688 756 85944 F204 E D E E I E T F Y K M L T Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 L210 I A G S A D T L S V D R L V Q
Chicken Gallus gallus Q2VRL0 637 72514 K149 S E D C T I F K K E H R T V Y
Frog Xenopus laevis Q32NH8 758 87399 T203 V L F Y K A L T Q R D E V L K
Zebra Danio Brachydanio rerio A5D6R3 784 89362 S210 L F K K C D R S C D G R L D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 T204 L P D D K N A T M T K E Q F T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 T212 V E F Y R I I T R R P D L Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W08 564 64926 H76 V K H H N V F H H H G L V H L
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 N284 F F Q L A D I N H N G L L N Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 97.5 79.9 N.A. 88 49.1 N.A. 46.7 26.7 48.5 52.3 N.A. 24.1 N.A. N.A. 37.3
Protein Similarity: 100 96.6 98.2 83 N.A. 92.2 66.1 N.A. 62 44.8 65.9 69.8 N.A. 38.2 N.A. N.A. 57.1
P-Site Identity: 100 100 100 6.6 N.A. 93.3 6.6 N.A. 26.6 6.6 6.6 53.3 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 100 26.6 N.A. 40 6.6 26.6 73.3 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.7 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. 37.9 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 15 8 8 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 8 36 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 15 8 0 50 8 0 0 8 36 8 0 8 0 % D
% Glu: 8 15 8 36 0 15 0 0 0 8 8 15 0 36 8 % E
% Phe: 8 43 15 0 0 0 15 8 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 8 0 0 0 0 0 22 0 0 0 29 % G
% His: 8 0 8 8 0 0 29 8 15 8 8 0 0 8 8 % H
% Ile: 8 0 0 0 8 15 15 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 36 8 15 0 0 8 8 8 8 0 0 0 8 % K
% Leu: 43 8 0 8 0 0 8 8 0 8 0 22 58 8 15 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 8 29 36 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 8 0 8 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 8 0 0 0 8 15 8 % Q
% Arg: 0 8 0 0 8 0 8 8 8 15 0 50 0 0 8 % R
% Ser: 8 0 0 15 0 0 0 36 8 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 15 22 0 8 0 0 15 0 8 % T
% Val: 22 0 0 0 0 8 0 0 8 8 0 0 15 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 15 0 0 0 0 8 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _