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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
21.82
Human Site:
S271
Identified Species:
36.92
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
S271
S
G
E
D
R
V
L
S
A
P
E
L
L
E
F
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S271
S
G
E
D
R
V
L
S
A
P
E
L
L
E
F
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
S267
S
G
E
D
R
V
L
S
A
P
E
L
L
E
F
Dog
Lupus familis
XP_548052
697
79208
D225
Q
H
E
L
M
T
L
D
G
F
M
M
Y
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
S267
S
G
E
D
R
V
L
S
A
S
E
L
L
E
F
Rat
Rattus norvegicus
P10688
756
85944
S229
A
G
S
A
E
T
L
S
V
E
R
L
V
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S234
A
D
P
K
M
A
H
S
L
I
E
R
Y
E
P
Chicken
Gallus gallus
Q2VRL0
637
72514
H172
D
Y
F
I
S
S
S
H
N
T
Y
L
V
S
D
Frog
Xenopus laevis
Q32NH8
758
87399
E226
G
K
K
L
T
L
L
E
F
V
D
F
L
Q
Q
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
T248
S
G
N
G
C
V
L
T
T
L
E
L
R
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
S244
K
G
K
Q
D
F
I
S
L
E
Q
F
I
Q
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
E235
D
D
Y
W
T
P
E
E
F
A
E
F
M
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
P99
S
D
T
N
S
P
L
P
M
S
G
Q
V
H
H
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
I310
N
R
K
E
V
N
M
I
W
S
K
F
T
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
13.3
N.A.
93.3
33.3
N.A.
20
6.6
13.3
46.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
93.3
46.6
N.A.
26.6
13.3
40
60
N.A.
53.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
8
0
0
29
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
22
0
29
8
0
0
8
0
0
8
0
0
8
8
% D
% Glu:
0
0
36
8
8
0
8
15
0
15
50
0
0
36
8
% E
% Phe:
0
0
8
0
0
8
0
0
15
8
0
29
0
0
50
% F
% Gly:
8
50
0
8
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
8
0
0
0
0
0
15
8
% H
% Ile:
0
0
0
8
0
0
8
8
0
8
0
0
8
0
0
% I
% Lys:
8
8
22
8
0
0
0
0
0
0
8
0
0
8
0
% K
% Leu:
0
0
0
15
0
8
65
0
15
8
0
50
36
8
8
% L
% Met:
0
0
0
0
15
0
8
0
8
0
8
8
8
0
0
% M
% Asn:
8
0
8
8
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
15
0
8
0
22
0
0
0
0
15
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
8
8
0
15
8
% Q
% Arg:
0
8
0
0
29
0
0
0
0
0
8
8
8
0
0
% R
% Ser:
43
0
8
0
15
8
8
50
0
22
0
0
0
8
0
% S
% Thr:
0
0
8
0
15
15
0
8
8
8
0
0
8
8
0
% T
% Val:
0
0
0
0
8
36
0
0
8
8
0
0
22
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
8
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _