KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
26.67
Human Site:
S349
Identified Species:
45.13
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
S349
P
L
A
H
Y
F
I
S
S
S
H
N
T
Y
L
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S349
P
L
A
H
Y
F
I
S
S
S
H
N
T
Y
L
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
S345
P
L
A
H
Y
F
I
S
S
S
H
N
T
Y
L
Dog
Lupus familis
XP_548052
697
79208
G301
L
D
C
W
E
G
P
G
G
E
P
I
I
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
S345
P
L
A
H
Y
F
I
S
S
S
H
N
T
Y
L
Rat
Rattus norvegicus
P10688
756
85944
S308
P
L
S
H
Y
L
V
S
S
S
H
N
T
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
I311
P
S
S
T
E
A
Y
I
R
A
L
S
R
G
C
Chicken
Gallus gallus
Q2VRL0
637
72514
L248
A
S
D
Y
P
V
V
L
S
L
E
N
H
C
S
Frog
Xenopus laevis
Q32NH8
758
87399
S302
P
L
C
H
Y
F
I
S
S
S
H
N
T
Y
L
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S325
P
L
A
H
Y
Y
I
S
S
S
H
N
T
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
N331
P
L
A
H
Y
Y
I
N
S
S
H
N
T
Y
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
N311
P
L
A
H
Y
F
I
N
S
S
H
N
T
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
E175
G
R
T
L
T
S
H
E
D
L
Q
K
C
L
T
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
A392
P
L
N
H
Y
F
I
A
S
S
H
N
T
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
6.6
N.A.
100
80
N.A.
6.6
13.3
93.3
93.3
N.A.
86.6
N.A.
N.A.
93.3
P-Site Similarity:
100
100
100
6.6
N.A.
100
93.3
N.A.
26.6
26.6
93.3
100
N.A.
100
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
86.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
50
0
0
8
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
0
8
8
8
% C
% Asp:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
15
0
0
8
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
8
8
0
0
0
0
8
0
% G
% His:
0
0
0
72
0
0
8
0
0
0
72
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
65
8
0
0
0
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
72
0
8
0
8
0
8
0
15
8
0
0
8
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
15
0
0
0
79
0
0
0
% N
% Pro:
79
0
0
0
8
0
8
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% R
% Ser:
0
15
15
0
0
8
0
50
79
72
0
8
0
0
8
% S
% Thr:
0
0
8
8
8
0
0
0
0
0
0
0
72
0
8
% T
% Val:
0
0
0
0
0
8
15
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
72
15
8
0
0
0
0
0
0
79
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _