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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD3 All Species: 33.03
Human Site: S366 Identified Species: 55.9
UniProt: Q8N3E9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3E9 NP_588614.1 789 89258 S366 S Q I G G P S S T E A Y V R A
Chimpanzee Pan troglodytes XP_001142960 788 88666 S366 S Q I G G P S S T E A Y V R A
Rhesus Macaque Macaca mulatta XP_001115230 785 88822 S362 S Q I G G P S S T E A Y I R A
Dog Lupus familis XP_548052 697 79208 F318 T L T S K I L F R D V V Q A V
Cat Felis silvestris
Mouse Mus musculus Q8K2J0 785 88588 S362 S Q I G G T S S T E A Y I R A
Rat Rattus norvegicus P10688 756 85944 S325 D Q L T G P S S T E A Y I R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 G328 V E L D C W D G S G N E P V I
Chicken Gallus gallus Q2VRL0 637 72514 Y265 Q Q E R I A Q Y L L N I L G D
Frog Xenopus laevis Q32NH8 758 87399 S319 D Q I R G Q S S I E G Y I R A
Zebra Danio Brachydanio rerio A5D6R3 784 89362 S342 D Q V T S A S S T E P Y I R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 S348 R Q I G G K S S V E M Y R Q T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 S328 D Q L R G P S S T E A Y I S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W08 564 64926 S192 K D N A F H V S D Y P V I I T
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 S409 K Q I A E T P S V E G Y I Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 97.5 79.9 N.A. 88 49.1 N.A. 46.7 26.7 48.5 52.3 N.A. 24.1 N.A. N.A. 37.3
Protein Similarity: 100 96.6 98.2 83 N.A. 92.2 66.1 N.A. 62 44.8 65.9 69.8 N.A. 38.2 N.A. N.A. 57.1
P-Site Identity: 100 100 93.3 0 N.A. 86.6 73.3 N.A. 0 6.6 60 53.3 N.A. 53.3 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 86.6 N.A. 20 13.3 66.6 66.6 N.A. 60 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 23.7 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. 37.9 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 15 0 0 0 0 43 0 0 8 58 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 8 0 8 0 0 8 0 8 8 0 0 0 0 8 % D
% Glu: 0 8 8 0 8 0 0 0 0 72 0 8 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 36 58 0 0 8 0 8 15 0 0 8 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 50 0 8 8 0 0 8 0 0 8 58 8 8 % I
% Lys: 15 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 22 0 0 0 8 0 8 8 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 15 0 0 0 0 % N
% Pro: 0 0 0 0 0 36 8 0 0 0 15 0 8 0 0 % P
% Gln: 8 79 0 0 0 8 8 0 0 0 0 0 8 15 0 % Q
% Arg: 8 0 0 22 0 0 0 0 8 0 0 0 8 50 0 % R
% Ser: 29 0 0 8 8 0 65 79 8 0 0 0 0 8 0 % S
% Thr: 8 0 8 15 0 15 0 0 50 0 0 0 0 0 15 % T
% Val: 8 0 8 0 0 0 8 0 15 0 8 15 15 8 15 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 8 0 72 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _