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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
13.33
Human Site:
S461
Identified Species:
22.56
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
S461
L
V
T
Q
A
L
D
S
P
N
P
E
E
L
P
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S461
L
V
T
Q
A
L
D
S
P
N
P
E
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
S457
L
V
T
Q
A
L
D
S
P
N
P
E
E
L
P
Dog
Lupus familis
XP_548052
697
79208
P396
L
V
K
G
K
K
L
P
A
A
R
S
E
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
S457
L
V
T
Q
A
L
D
S
Q
N
P
E
E
L
P
Rat
Rattus norvegicus
P10688
756
85944
G420
L
L
D
Q
P
L
D
G
V
T
T
S
L
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
F406
V
D
G
M
V
N
N
F
P
S
P
E
Q
L
K
Chicken
Gallus gallus
Q2VRL0
637
72514
L343
E
T
D
E
K
T
P
L
Y
P
K
S
G
S
S
Frog
Xenopus laevis
Q32NH8
758
87399
G414
L
V
M
S
T
L
D
G
R
I
P
V
R
L
P
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
D437
L
L
A
K
P
L
S
D
L
P
L
K
Q
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
D445
L
L
K
E
P
L
P
D
H
P
L
D
P
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
L422
K
L
Y
T
N
N
N
L
H
N
E
A
A
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
K270
T
T
R
T
P
T
V
K
E
T
S
W
N
R
V
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
L505
V
G
T
R
T
D
K
L
P
S
P
R
E
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
20
N.A.
93.3
26.6
N.A.
26.6
0
46.6
26.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
93.3
33.3
N.A.
53.3
6.6
46.6
53.3
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
29
0
0
0
8
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
0
0
8
43
15
0
0
0
8
0
8
0
% D
% Glu:
8
0
0
15
0
0
0
0
8
0
8
36
43
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
8
8
8
0
0
0
15
0
0
0
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
15
8
15
8
8
8
0
0
8
8
0
0
15
% K
% Leu:
65
29
0
0
0
58
8
22
8
0
15
0
8
58
8
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
15
15
0
0
36
0
0
8
0
0
% N
% Pro:
0
0
0
0
29
0
15
8
36
22
50
0
8
8
50
% P
% Gln:
0
0
0
36
0
0
0
0
8
0
0
0
15
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
8
0
8
8
8
8
0
% R
% Ser:
0
0
0
8
0
0
8
29
0
15
8
22
0
8
15
% S
% Thr:
8
15
36
15
15
15
0
0
0
15
8
0
0
0
0
% T
% Val:
15
43
0
0
8
0
8
0
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _