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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
17.58
Human Site:
S489
Identified Species:
29.74
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
S489
K
K
L
P
A
A
R
S
E
D
G
R
A
L
S
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S489
K
K
L
P
A
A
R
S
E
D
G
R
A
L
S
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
S485
K
K
L
P
A
A
R
S
E
D
G
R
A
L
S
Dog
Lupus familis
XP_548052
697
79208
E419
E
E
E
E
E
E
E
E
P
E
A
T
E
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
S485
K
K
L
P
A
A
R
S
E
D
G
R
I
L
S
Rat
Rattus norvegicus
P10688
756
85944
G450
G
G
L
L
P
A
G
G
E
N
G
S
E
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
G434
L
D
G
P
E
A
A
G
T
D
A
A
Y
V
S
Chicken
Gallus gallus
Q2VRL0
637
72514
A366
S
P
P
P
R
K
K
A
K
V
K
K
M
K
I
Frog
Xenopus laevis
Q32NH8
758
87399
E446
R
L
E
D
S
L
E
E
Q
P
D
D
S
L
G
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
D478
T
S
F
T
N
S
S
D
E
E
S
V
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
W483
E
K
V
E
L
E
L
W
L
K
G
E
L
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
T452
L
P
P
S
A
A
T
T
E
D
D
G
E
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
V293
K
D
M
E
S
E
A
V
G
Y
R
D
L
I
A
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
S540
E
P
F
P
S
S
F
S
S
S
Y
E
S
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
0
N.A.
93.3
26.6
N.A.
26.6
6.6
6.6
13.3
N.A.
13.3
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
20
N.A.
93.3
40
N.A.
33.3
33.3
33.3
26.6
N.A.
33.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
36
50
15
8
0
0
15
8
29
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
8
0
0
0
8
0
43
15
15
0
0
0
% D
% Glu:
22
8
15
22
15
22
15
15
50
15
0
15
22
0
0
% E
% Phe:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
8
15
8
0
43
8
0
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% I
% Lys:
36
36
0
0
0
8
8
0
8
8
8
8
0
15
0
% K
% Leu:
15
8
36
8
8
8
8
0
8
0
0
0
15
36
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
22
15
50
8
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
8
0
29
0
0
0
8
29
0
0
8
% R
% Ser:
8
8
0
8
22
15
8
36
8
8
8
8
15
0
43
% S
% Thr:
8
0
0
8
0
0
8
8
8
0
0
8
0
0
15
% T
% Val:
0
0
8
0
0
0
0
8
0
8
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _