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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
25.45
Human Site:
S559
Identified Species:
43.08
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
S559
P
C
Q
V
S
S
L
S
E
R
K
A
K
K
L
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S559
P
C
Q
V
S
S
L
S
E
R
K
A
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
S555
P
C
Q
V
S
S
L
S
E
R
K
A
K
K
L
Dog
Lupus familis
XP_548052
697
79208
I475
E
R
K
A
K
K
L
I
R
E
A
G
N
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
S555
S
C
T
V
G
S
L
S
E
R
K
A
R
K
F
Rat
Rattus norvegicus
P10688
756
85944
S524
F
Y
E
M
A
S
F
S
E
S
R
A
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S504
F
Y
E
M
S
S
L
S
E
N
K
A
L
R
L
Chicken
Gallus gallus
Q2VRL0
637
72514
Q422
F
V
K
H
A
A
N
Q
F
V
S
H
T
S
R
Frog
Xenopus laevis
Q32NH8
758
87399
T517
L
Y
E
M
S
S
V
T
E
Y
K
A
R
K
L
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S536
P
S
V
I
T
S
F
S
E
N
E
A
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A581
A
H
N
M
S
S
F
A
E
S
A
G
M
N
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
G525
C
H
Q
M
S
S
F
G
E
A
K
A
F
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
N349
L
V
R
F
T
Q
R
N
L
V
R
I
Y
P
K
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
R618
H
C
F
S
L
N
E
R
K
V
E
Y
M
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
6.6
N.A.
66.6
33.3
N.A.
53.3
0
46.6
46.6
N.A.
20
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
13.3
N.A.
73.3
66.6
N.A.
73.3
20
80
66.6
N.A.
33.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
15
8
0
8
0
8
15
65
0
0
0
% A
% Cys:
8
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
22
0
0
0
8
0
72
8
15
0
0
0
0
% E
% Phe:
22
0
8
8
0
0
29
0
8
0
0
0
8
0
15
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
15
0
8
0
% G
% His:
8
15
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
0
8
0
8
0
% I
% Lys:
0
0
15
0
8
8
0
0
8
0
50
0
22
43
15
% K
% Leu:
15
0
0
0
8
0
43
0
8
0
0
0
22
0
58
% L
% Met:
0
0
0
36
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
0
0
8
0
0
8
8
8
0
15
0
0
8
8
0
% N
% Pro:
29
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
29
0
0
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
0
8
8
8
29
15
0
15
15
8
% R
% Ser:
8
8
0
8
50
72
0
50
0
15
8
0
0
15
0
% S
% Thr:
0
0
8
0
15
0
0
8
0
0
0
0
8
0
0
% T
% Val:
0
15
8
29
0
0
8
0
0
22
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
22
0
0
0
0
0
0
0
8
0
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _