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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
20
Human Site:
S682
Identified Species:
33.85
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
S682
L
N
A
E
K
P
H
S
I
V
D
P
L
V
R
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S681
L
N
A
E
K
P
H
S
I
V
D
P
L
V
R
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
S678
L
N
A
E
K
P
H
S
I
V
D
P
L
V
R
Dog
Lupus familis
XP_548052
697
79208
V596
N
S
I
V
D
P
L
V
R
V
E
I
H
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
S678
L
N
A
E
K
P
S
S
I
V
D
P
L
V
R
Rat
Rattus norvegicus
P10688
756
85944
N647
Q
L
P
K
V
N
K
N
K
N
S
I
V
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
K627
Q
Q
L
P
K
V
N
K
S
K
N
S
I
V
D
Chicken
Gallus gallus
Q2VRL0
637
72514
Y543
P
L
V
Q
L
E
I
Y
G
V
P
E
D
Q
A
Frog
Xenopus laevis
Q32NH8
758
87399
S640
Q
L
P
K
V
E
N
S
K
E
G
S
I
V
D
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S663
I
N
T
D
K
P
N
S
I
V
D
P
Q
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
G704
F
L
S
D
K
K
V
G
T
Y
V
E
V
D
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
V648
K
P
S
G
S
K
E
V
I
D
P
Y
V
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
T470
I
A
G
V
P
R
D
T
V
S
Y
R
T
E
T
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
R755
L
N
D
T
S
P
S
R
N
N
T
N
S
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
13.3
N.A.
93.3
0
N.A.
13.3
6.6
13.3
60
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
20
N.A.
33.3
13.3
33.3
80
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
29
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
15
8
0
8
0
0
8
36
0
8
15
15
% D
% Glu:
0
0
0
29
0
15
8
0
0
8
8
15
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
8
0
0
0
8
8
0
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
22
0
0
0
0
0
8
0
0
% H
% Ile:
15
0
8
0
0
0
8
0
43
0
0
15
15
0
0
% I
% Lys:
8
0
0
15
50
15
8
8
15
8
0
0
0
8
0
% K
% Leu:
36
29
8
0
8
0
8
0
0
0
0
0
29
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
43
0
0
0
8
22
8
8
15
8
8
0
0
0
% N
% Pro:
8
8
15
8
8
50
0
0
0
0
15
36
0
0
8
% P
% Gln:
22
8
0
8
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
29
% R
% Ser:
0
8
15
0
15
0
15
43
8
8
8
15
8
0
0
% S
% Thr:
0
0
8
8
0
0
0
8
8
0
8
0
8
0
8
% T
% Val:
0
0
8
15
15
8
8
15
8
50
8
0
22
50
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _