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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
11.21
Human Site:
T168
Identified Species:
18.97
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
T168
Q
R
W
V
R
G
L
T
K
L
R
A
R
L
D
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
T168
Q
R
W
V
R
G
L
T
K
L
R
A
R
L
D
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
T164
Q
R
W
V
R
G
L
T
K
L
R
A
R
L
D
Dog
Lupus familis
XP_548052
697
79208
R137
R
L
D
A
M
S
Q
R
E
R
L
D
Q
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
A164
Q
R
W
V
R
G
L
A
K
L
R
A
R
L
D
Rat
Rattus norvegicus
P10688
756
85944
Q139
S
G
S
M
D
Q
R
Q
K
L
Q
H
W
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
K145
K
D
N
K
M
S
F
K
E
V
K
N
F
L
K
Chicken
Gallus gallus
Q2VRL0
637
72514
E84
E
I
F
C
A
Y
S
E
N
R
K
N
L
A
D
Frog
Xenopus laevis
Q32NH8
758
87399
W138
R
K
D
L
M
D
Q
W
I
C
D
W
F
Q
K
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
R145
E
R
W
V
R
G
I
R
T
L
K
D
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
T139
Q
K
N
L
R
L
I
T
H
N
N
R
A
T
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
D147
M
D
A
F
R
Q
A
D
V
D
R
D
G
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
C11
S
F
K
V
C
F
C
C
S
R
S
F
K
E
K
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
E219
G
L
V
K
L
R
R
E
L
M
E
S
I
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
0
N.A.
93.3
13.3
N.A.
6.6
6.6
0
46.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
93.3
33.3
N.A.
33.3
26.6
20
73.3
N.A.
46.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
8
8
0
0
0
29
8
8
0
% A
% Cys:
0
0
0
8
8
0
8
8
0
8
0
0
0
0
0
% C
% Asp:
0
15
15
0
8
8
0
8
0
8
8
22
0
0
36
% D
% Glu:
15
0
0
0
0
0
0
15
15
0
8
0
0
8
0
% E
% Phe:
0
8
8
8
0
8
8
0
0
0
0
8
15
0
0
% F
% Gly:
8
8
0
0
0
36
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% H
% Ile:
0
8
0
0
0
0
15
0
8
0
0
0
8
8
0
% I
% Lys:
8
15
8
15
0
0
0
8
36
0
22
0
8
0
22
% K
% Leu:
0
15
0
15
8
8
29
0
8
43
8
0
8
43
8
% L
% Met:
8
0
0
8
22
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
8
8
8
15
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
36
0
0
0
0
15
15
8
0
0
8
0
8
8
0
% Q
% Arg:
15
36
0
0
50
8
15
15
0
22
36
8
36
0
0
% R
% Ser:
15
0
8
0
0
15
8
0
8
0
8
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
29
8
0
0
0
0
15
0
% T
% Val:
0
0
8
43
0
0
0
0
8
8
0
0
0
8
8
% V
% Trp:
0
0
36
0
0
0
0
8
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _