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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD3 All Species: 11.21
Human Site: T168 Identified Species: 18.97
UniProt: Q8N3E9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3E9 NP_588614.1 789 89258 T168 Q R W V R G L T K L R A R L D
Chimpanzee Pan troglodytes XP_001142960 788 88666 T168 Q R W V R G L T K L R A R L D
Rhesus Macaque Macaca mulatta XP_001115230 785 88822 T164 Q R W V R G L T K L R A R L D
Dog Lupus familis XP_548052 697 79208 R137 R L D A M S Q R E R L D Q Y P
Cat Felis silvestris
Mouse Mus musculus Q8K2J0 785 88588 A164 Q R W V R G L A K L R A R L D
Rat Rattus norvegicus P10688 756 85944 Q139 S G S M D Q R Q K L Q H W I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 K145 K D N K M S F K E V K N F L K
Chicken Gallus gallus Q2VRL0 637 72514 E84 E I F C A Y S E N R K N L A D
Frog Xenopus laevis Q32NH8 758 87399 W138 R K D L M D Q W I C D W F Q K
Zebra Danio Brachydanio rerio A5D6R3 784 89362 R145 E R W V R G I R T L K D R V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 T139 Q K N L R L I T H N N R A T N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 D147 M D A F R Q A D V D R D G T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W08 564 64926 C11 S F K V C F C C S R S F K E K
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 E219 G L V K L R R E L M E S I L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 97.5 79.9 N.A. 88 49.1 N.A. 46.7 26.7 48.5 52.3 N.A. 24.1 N.A. N.A. 37.3
Protein Similarity: 100 96.6 98.2 83 N.A. 92.2 66.1 N.A. 62 44.8 65.9 69.8 N.A. 38.2 N.A. N.A. 57.1
P-Site Identity: 100 100 100 0 N.A. 93.3 13.3 N.A. 6.6 6.6 0 46.6 N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 93.3 33.3 N.A. 33.3 26.6 20 73.3 N.A. 46.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.7 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. 37.9 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 0 8 8 0 0 0 29 8 8 0 % A
% Cys: 0 0 0 8 8 0 8 8 0 8 0 0 0 0 0 % C
% Asp: 0 15 15 0 8 8 0 8 0 8 8 22 0 0 36 % D
% Glu: 15 0 0 0 0 0 0 15 15 0 8 0 0 8 0 % E
% Phe: 0 8 8 8 0 8 8 0 0 0 0 8 15 0 0 % F
% Gly: 8 8 0 0 0 36 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % H
% Ile: 0 8 0 0 0 0 15 0 8 0 0 0 8 8 0 % I
% Lys: 8 15 8 15 0 0 0 8 36 0 22 0 8 0 22 % K
% Leu: 0 15 0 15 8 8 29 0 8 43 8 0 8 43 8 % L
% Met: 8 0 0 8 22 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 15 0 0 0 0 0 8 8 8 15 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 36 0 0 0 0 15 15 8 0 0 8 0 8 8 0 % Q
% Arg: 15 36 0 0 50 8 15 15 0 22 36 8 36 0 0 % R
% Ser: 15 0 8 0 0 15 8 0 8 0 8 8 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 29 8 0 0 0 0 15 0 % T
% Val: 0 0 8 43 0 0 0 0 8 8 0 0 0 8 8 % V
% Trp: 0 0 36 0 0 0 0 8 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _